Literature DB >> 24127124

Development of azo-based fluorescent probes to detect different levels of hypoxia.

Wen Piao1, Satoru Tsuda, Yuji Tanaka, Satoshi Maeda, Fengyi Liu, Shodai Takahashi, Yu Kushida, Toru Komatsu, Tasuku Ueno, Takuya Terai, Toru Nakazawa, Masanobu Uchiyama, Keiji Morokuma, Tetsuo Nagano, Kenjiro Hanaoka.   

Abstract

Let it shine: New hypoxia-sensitive fluorescent probes were developed; they consist of a rhodamine moiety with an azo group directly conjugated to the fluorophore. Because of an ultrafast conformational change around the NN bond, the compounds are nonfluorescent under normoxia. However, under hypoxia, the azo group is reduced, and a strongly fluorescent rhodamine derivative is released.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  azo compounds; bioorganic chemistry; fluorescent probes; imaging agents; oxygen concentration

Mesh：

Substances：

Year:  2013        PMID： 24127124     DOI： 10.1002/anie.201305784

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  32 in total

1.  In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation.

Authors:  Jian Cao; James Campbell; Li Liu; Ralph P Mason; Alexander R Lippert
Journal:  Anal Chem       Date:  2016-04-15       Impact factor: 6.986

2.  Inhibition of WNT/β-catenin signaling under serum starvation and hypoxia induces adipocytic transdifferentiation in human leiomyoma cells.

Authors:  Hiroshi Harada; Yojiro Tsuda; Kei Yabuki; Eisuke Shiba; Kazuyoshi Uchihashi; Atsuji Matsuyama; Yoshihisa Fujino; Toru Hachisuga; Masanori Hisaoka
Journal:  Lab Invest       Date:  2018-01-18       Impact factor: 5.662

3.  Luminescent Probe Based Techniques for Hypoxia Imaging.

Authors:  Sana Sandhu; LeNaiya Kydd; Justyn Jaworski
Journal:  J Nanomed Res       Date:  2017-11-20

4.  Applications of azo-based probes for imaging retinal hypoxia.

Authors:  Md Imam Uddin; Stephanie M Evans; Jason R Craft; Lawrence J Marnett; Md Jashim Uddin; Ashwath Jayagopal
Journal:  ACS Med Chem Lett       Date:  2015-02-12       Impact factor: 4.345

5.  Recapitulating Tumor Hypoxia in a Cleanroom-Free, Liquid-Pinning-Based Microfluidic Tumor Model.

Authors:  Jeong Min Oh; Hydari Masuma Begum; Yao Lucia Liu; Yuwei Ren; Keyue Shen
Journal:  ACS Biomater Sci Eng       Date:  2022-06-09

6.  Hypoxia-targeted siRNA delivery.

Authors:  F Perche; S Biswas; T Wang; L Zhu; V P Torchilin
Journal:  Angew Chem Int Ed Engl       Date:  2014-02-19       Impact factor: 15.336

7.  Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo.

Authors:  Yuming Zhang; Wenxuan Zhao; Yuncong Chen; Hao Yuan; Hongbao Fang; Shankun Yao; Changli Zhang; Hongxia Xu; Nan Li; Zhipeng Liu; Zijian Guo; Qingshun Zhao; Yong Liang; Weijiang He
Journal:  Nat Commun       Date:  2021-05-13       Impact factor: 14.919

8.  Ratiometric Molecular Probes Based on Dual Emission of a Blue Fluorescent Coumarin and a Red Phosphorescent Cationic Iridium(III) Complex for Intracellular Oxygen Sensing.

Authors:  Toshitada Yoshihara; Saori Murayama; Seiji Tobita
Journal:  Sensors (Basel)       Date:  2015-06-09       Impact factor: 3.576

9.  Azo-Based Iridium(III) Complexes as Multicolor Phosphorescent Probes to Detect Hypoxia in 3D Multicellular Tumor Spheroids.

Authors:  Lingli Sun; Guanying Li; Xiang Chen; Yu Chen; Chengzhi Jin; Liangnian Ji; Hui Chao
Journal:  Sci Rep       Date:  2015-10-01       Impact factor: 4.379

10.  Self-assembled amphiphilic fluorescent probe: detecting pH-fluctuations within cancer cells and tumour tissues.

Authors:  Soo Yeon Kim; Arup Podder; Hyunseung Lee; Youn-Joo Cho; Eun Hee Han; Sabina Khatun; Jonathan L Sessler; Kwan Soo Hong; Sankarprasad Bhuniya
Journal:  Chem Sci       Date:  2020-08-28       Impact factor: 9.825
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.