OBJECTIVE: Development of left ventricular hypertrophy (LVH) is a multifactorial phenomenon. We retrospectively assessed the risk factors for LVH in patients with recent diagnosis of essential hypertension. METHODS: We analysed 1518 participants with recent diagnosis of essential hypertension (≤2 years). The duration of hypertension was established after cross-checking the patients' history and the records of the general practitioners'. The following cardiovascular (CV) risk factors were considered: age (men >55 years, women >65 years), SBP >140 mmHg, DBP >90 mmHg, obesity, diabetes, hypercholesterolemia, low or high-density lipoprotein (HDL)-cholesterol (men <40 m/dl, women <50 mg/dl), and chronic kidney disease (CKD). RESULTS: Age, prevalence of metabolic diseases, CKD, and the severity of hypertension were higher in patients with LVH. One hundred twenty-two (8%) patients did not have CV risk factors, whereas 288 (19%), 472 (31.1%), 351 (23.1%) and 285 (18.8%) patients had one, two, three and more than three CV risk factors, respectively. At univariate analysis, CV risk factors for LVH where found to be sex, age, SBP, low HDL-cholesterol, obesity, diabetes, CKD, and metabolic syndrome. In the multivariate analysis, the independent predictors of LVH were found to be sex, age, SBP, obesity and diabetes. A significant correlation was found between indexed left ventricular mass and body mass index (r(2) = 0.167), age (r(2) = 0.077) and SBP (r (2)= 0.055). CONCLUSION: This study reveals that, in patients with recent diagnosis of essential hypertension obesity represents the most important modifiable CV risk factor for LVH.
OBJECTIVE: Development of left ventricular hypertrophy (LVH) is a multifactorial phenomenon. We retrospectively assessed the risk factors for LVH in patients with recent diagnosis of essential hypertension. METHODS: We analysed 1518 participants with recent diagnosis of essential hypertension (≤2 years). The duration of hypertension was established after cross-checking the patients' history and the records of the general practitioners'. The following cardiovascular (CV) risk factors were considered: age (men >55 years, women >65 years), SBP >140 mmHg, DBP >90 mmHg, obesity, diabetes, hypercholesterolemia, low or high-density lipoprotein (HDL)-cholesterol (men <40 m/dl, women <50 mg/dl), and chronic kidney disease (CKD). RESULTS: Age, prevalence of metabolic diseases, CKD, and the severity of hypertension were higher in patients with LVH. One hundred twenty-two (8%) patients did not have CV risk factors, whereas 288 (19%), 472 (31.1%), 351 (23.1%) and 285 (18.8%) patients had one, two, three and more than three CV risk factors, respectively. At univariate analysis, CV risk factors for LVH where found to be sex, age, SBP, low HDL-cholesterol, obesity, diabetes, CKD, and metabolic syndrome. In the multivariate analysis, the independent predictors of LVH were found to be sex, age, SBP, obesity and diabetes. A significant correlation was found between indexed left ventricular mass and body mass index (r(2) = 0.167), age (r(2) = 0.077) and SBP (r (2)= 0.055). CONCLUSION: This study reveals that, in patients with recent diagnosis of essential hypertension obesity represents the most important modifiable CV risk factor for LVH.
Authors: Amira Esmat El Tantawy; Fatina Fadel; Safaa M Abdelrahman; Marwa Nabhan; Reem Ibrahim; Aya M Fattouh; Shaimaa El Sayed; Khaled Mohamed ElKhashab; Peter Afdal; Antoine Fakhry AbdelMassih Journal: Cardiovasc Endocrinol Metab Date: 2019-11-13
Authors: Xin Jiang; Yi Guo; Yue Zhao; Xia Gao; Dan Peng; Hui Zhang; Wuhong Deng; Wen Fu; Na Qin; Ruizhen Chang; Brad Manor; Lewis A Lipsitz; Junhong Zhou Journal: Front Cardiovasc Med Date: 2021-02-26
Authors: Marta Rojek; Marek Rajzer; Wiktoria Wojciechowska; Jerzy Gąsowski; Tomasz Pizoń; Danuta Czarnecka Journal: Medicine (Baltimore) Date: 2017-12 Impact factor: 1.889
Authors: Francesco Giallauria; Teresa Strisciuglio; Gianluigi Cuomo; Anna Di Lorenzo; Andrea D'Angelo; Mario Volpicelli; Raffaele Izzo; Maria Virginia Manzi; Emanuele Barbato; Carmine Morisco Journal: High Blood Press Cardiovasc Prev Date: 2021-11-01