An antiserum to locust adipokinetic hormone reveals a novel peptidergic system in the rat central nervous system.

Using an antiserum to locust adipokinetic hormone I, a novel peptidergic system was identified in the rat central nervous system. Immunoreactive fibers were present in the hypothalamic median eminence and periventricular nucleus and the spinal cord dorsal horn, intermediolateral cell column and sacral parasympathetic nucleus. Immunoreactive cells were present in the dorsal gray commissure of lumbosacral spinal cord, the hypothalamic periventricular nucleus and cerebral cortex.