Literature DB >> 24125598

Snake bites and hemostasis/thrombosis.

Ryan J R McCleary1, R Manjunatha Kini.   

Abstract

Snake venom toxins have evolved to affect many prey physiological systems including hemostasis and thrombosis. These toxins belong to a diverse array of protein families and can initiate or inhibit multiple stages of the coagulation pathway or platelet aggregation with incredible specificity. Such specificity toward vertebrate molecular targets has made them extremely useful for diagnosis of human diseases or as molecular scalpels in physiological studies. The large number of yet-to-be characterized venoms provides a vast potential source of novel toxins and subsequent cardiovascular therapeutics and diagnostic agents.
© 2013.

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Year:  2013        PMID: 24125598     DOI: 10.1016/j.thromres.2013.09.031

Source DB:  PubMed          Journal:  Thromb Res        ISSN: 0049-3848            Impact factor:   3.944


  11 in total

Review 1.  Modifications of natural peptides for nanoparticle and drug design.

Authors:  Andrew P Jallouk; Rohun U Palekar; Hua Pan; Paul H Schlesinger; Samuel A Wickline
Journal:  Adv Protein Chem Struct Biol       Date:  2015-03-12       Impact factor: 3.507

2.  Metabolites from Induratia spp. modulating key enzymes in human hemostasis.

Authors:  Mauro Guilherme Barros Cardoso; Marcus Vinicius Cardoso Trento; Pedro Henrique Souza Cesar; Silvana Marcussi; Patrícia Gomes Cardoso
Journal:  Arch Microbiol       Date:  2021-12-18       Impact factor: 2.552

3.  An antivenin resistant, IVIg-corticosteroids responsive viper induced thrombocytopenia.

Authors:  Matteo Turetta; Fabio Del Ben; Donatella Londero; Agostino Steffan; Pierpaolo Pillinini
Journal:  Toxicol Rep       Date:  2022-03-29

4.  Southern copperhead venom enhances tissue-type plasminogen activator induced fibrinolysis but does not directly lyse human plasma thrombi.

Authors:  Vance G Nielsen
Journal:  J Thromb Thrombolysis       Date:  2016-07       Impact factor: 2.300

5.  Purification and characterization of tenerplasminin-1, a serine peptidase inhibitor with antiplasmin activity from the coral snake (Micrurus tener tener) venom.

Authors:  Jeilyn Vivas; Carlos Ibarra; Ana M Salazar; Ana G C Neves-Ferreira; Elda E Sánchez; Jonás Perales; Alexis Rodríguez-Acosta; Belsy Guerrero
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2015-09-28       Impact factor: 3.228

6.  Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib.

Authors:  Taline D Kazandjian; Arif Arrahman; Kristina B M Still; Govert W Somsen; Freek J Vonk; Nicholas R Casewell; Mark C Wilkinson; Jeroen Kool
Journal:  Toxins (Basel)       Date:  2021-04-23       Impact factor: 4.546

7.  Risk factor, monitoring, and treatment for snakebite induced coagulopathy: a multicenter retrospective study.

Authors:  Yong Jun Jeon; Jong Wan Kim; SungGil Park; Dong Woo Shin
Journal:  Acute Crit Care       Date:  2019-11-18

8.  Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors.

Authors:  Gloria Maria da Silva; Daniel Henrique Berto de Souza; Karoline B Waitman; Matteo Celano Ebram; Melissa R Fessel; Iuliu Cezar Zainescu; Fernanda C Portaro; Montse Heras; Sonia A de Andrade
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2021-01-15

9.  Gene expression profiling of the venom gland from the Venezuelan mapanare (Bothrops colombiensis) using expressed sequence tags (ESTs).

Authors:  Montamas Suntravat; Néstor L Uzcategui; Chairat Atphaisit; Thomas J Helmke; Sara E Lucena; Elda E Sánchez; Alexis Rodríguez Acosta
Journal:  BMC Mol Biol       Date:  2016-03-05       Impact factor: 2.946

Review 10.  Metalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction Sites.

Authors:  R Manjunatha Kini; Cho Yeow Koh
Journal:  Toxins (Basel)       Date:  2016-09-29       Impact factor: 4.546

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