| Literature DB >> 24125569 |
Haifeng Li1, Fangli Ma, Minghua Hu, Chung Wah Ma, Lingyun Xiao, Ju Zhang, Yanxia Xiang, Zebo Huang.
Abstract
Recent studies have uncovered important aging clues, including free radicals, inflammation, telomeres, and life span pathways. Strategies to regulate aging-associated signaling pathways are expected to be effective in the delay and prevention of age-related disorders. For example, herbal polysaccharides with considerable anti-oxidant and anti-inflammation capacities have been shown to be beneficial in aging and age-related neurodegenerative diseases. Polysaccharides capable of reducing cellular senescence and modulating life span via telomere and insulin pathways have also been found to have the potential to inhibit protein aggregation and aggregation-associated neurodegeneration. Here we present the current status of polysaccharides in anti-aging and anti-neurodegenerative studies.Entities:
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Year: 2014 PMID： 24125569 PMCID： PMC3995358 DOI： 10.1089/rej.2013.1513
Source DB: PubMed Journal: Rejuvenation Res ISSN： 1549-1684 Impact factor: 4.663