Literature DB >> 24124228

Are short telomeres predictive of advanced cancer?

Jerry W Shay1.   

Abstract

The combination of variable telomere length in cancer cells and shorter telomere length in cancer-associated stromal cells strongly correlates with progression to prostate cancer metastasis and cancer death. The implication is that telomere length measurements have potential not only as prognostic indicators of prostate cancer outcomes but also as risk stratification enrichment biomarkers for individualized therapeutic interventions. ©2013 AACR.

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Year:  2013        PMID： 24124228      PMCID： PMC4163052          DOI： 10.1158/2159-8290.CD-13-0506

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  10 in total

1.  Implications of mapping the human telomerase gene (hTERT) as the most distal gene on chromosome 5p.

Authors:  J W Shay; W E Wright
Journal:  Neoplasia       Date:  2000 May-Jun       Impact factor: 5.715

2.  Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination.

Authors:  Nuno M V Gomes; Oliver A Ryder; Marlys L Houck; Suellen J Charter; William Walker; Nicholas R Forsyth; Steven N Austad; Chris Venditti; Mark Pagel; Jerry W Shay; Woodring E Wright
Journal:  Aging Cell       Date:  2011-06-01       Impact factor: 9.304

3.  Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis.

Authors:  A M De Marzo; V L Marchi; J I Epstein; W G Nelson
Journal:  Am J Pathol       Date:  1999-12       Impact factor: 4.307

4.  Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis.

Authors:  Alan K Meeker; Jessica L Hicks; Elizabeth A Platz; Gerrun E March; Christina J Bennett; Michael J Delannoy; Angelo M De Marzo
Journal:  Cancer Res       Date:  2002-11-15       Impact factor: 12.701

5.  Telomere length and risk of incident cancer and cancer mortality.

Authors:  Peter Willeit; Johann Willeit; Agnes Mayr; Siegfried Weger; Friedrich Oberhollenzer; Anita Brandstätter; Florian Kronenberg; Stefan Kiechl
Journal:  JAMA       Date:  2010-07-07       Impact factor: 56.272

Review 6.  Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.

Authors:  Tamara Tchkonia; Yi Zhu; Jan van Deursen; Judith Campisi; James L Kirkland
Journal:  J Clin Invest       Date:  2013-03-01       Impact factor: 14.808

7.  The effects of telomerase inhibition on prostate tumor-initiating cells.

Authors:  Calin O Marian; Woodring E Wright; Jerry W Shay
Journal:  Int J Cancer       Date:  2010-07-15       Impact factor: 7.396

Review 8.  Prostate tumor-initiating cells: a new target for telomerase inhibition therapy?

Authors:  Calin O Marian; Jerry W Shay
Journal:  Biochim Biophys Acta       Date:  2009-03-02

9.  Telomerase activity: a prevalent marker of malignant human prostate tissue.

Authors:  H J Sommerfeld; A K Meeker; M A Piatyszek; G S Bova; J W Shay; D S Coffey
Journal:  Cancer Res       Date:  1996-01-01       Impact factor: 12.701

10.  Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model.

Authors:  Benjamin K Canales; Yingming Li; Melissa G Thompson; Joseph M Gleason; Zhi Chen; Bahaa Malaeb; David R Corey; Brittney-Shea Herbert; Jerry W Shay; Kenneth S Koeneman
Journal:  Urol Oncol       Date:  2006 Mar-Apr       Impact factor: 3.498
  10 in total
  9 in total

1.  Recent advances of Blood telomere length (BTL) shortening: A potential biomarker for development of cancer.

Authors:  Paramita Mandal
Journal:  Pathol Oncol Res       Date:  2018-06-08       Impact factor: 3.201

2.  A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT.

Authors:  Gregory A Hosler; Teresa Davoli; Ilgen Mender; Brandon Litzner; Jaehyuk Choi; Payal Kapur; Jerry W Shay; Richard C Wang
Journal:  J Cutan Pathol       Date:  2014-12-11       Impact factor: 1.587

Review 3.  Telomerase gene therapy: a remission toward cancer.

Authors:  Sameer Quazi
Journal:  Med Oncol       Date:  2022-04-16       Impact factor: 3.064

Review 4.  Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.

Authors:  Mohammad A Jafri; Shakeel A Ansari; Mohammed H Alqahtani; Jerry W Shay
Journal:  Genome Med       Date:  2016-06-20       Impact factor: 11.117

5.  Milk Fat Intake and Telomere Length in U.S. Women and Men: The Role of the Milk Fat Fraction.

Authors:  Larry A Tucker
Journal:  Oxid Med Cell Longev       Date:  2019-10-28       Impact factor: 6.543

Review 6.  Is There an Interconnection between Epithelial-Mesenchymal Transition (EMT) and Telomere Shortening in Aging?

Authors:  Siti A M Imran; Muhammad Dain Yazid; Ruszymah Bt Hj Idrus; Manira Maarof; Abid Nordin; Rabiatul Adawiyah Razali; Yogeswaran Lokanathan
Journal:  Int J Mol Sci       Date:  2021-04-09       Impact factor: 5.923

7.  An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

Authors:  Zhifen Zhou; Yujing Li; Huimin Xu; Xiaowei Xie; Zibin He; Song Lin; Ruofei Li; Shouheng Jin; Jun Cui; Hai Hu; Feng Liu; Su Wu; Wenbin Ma; Zhou Songyang
Journal:  iScience       Date:  2022-01-25

Review 8.  Regulation of Gene Expression by Telomere Position Effect.

Authors:  Kyung-Ha Lee; Do-Yeon Kim; Wanil Kim
Journal:  Int J Mol Sci       Date:  2021-11-26       Impact factor: 5.923

Review 9.  Telomeric Repeat-Containing RNA (TERRA): A Review of the Literature and First Assessment in Cutaneous T-Cell Lymphomas.

Authors:  Alain Chebly; Joana Ropio; Lyla Baldasseroni; Martina Prochazkova-Carlotti; Yamina Idrissi; Jacky Ferrer; Chantal Farra; Marie Beylot-Barry; Jean-Philippe Merlio; Edith Chevret
Journal:  Genes (Basel)       Date:  2022-03-18       Impact factor: 4.096
  9 in total

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