Literature DB >> 24123787

Tailored glycopolymers as anticoagulant heparin mimetics.

Young In Oh1, Gloria J Sheng, Shuh-Kuen Chang, Linda C Hsieh-Wilson.   

Abstract

Entities:  

Keywords:  anticoagulant; biomimetic synthesis; drug discovery; glycopolymers; heparin

Mesh:

Substances:

Year:  2013        PMID: 24123787      PMCID: PMC3943734          DOI: 10.1002/anie.201306968

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  30 in total

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2.  Synthesis and activity of a new generation of ruthenium-based olefin metathesis catalysts coordinated with 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ligands.

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3.  Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins.

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4.  Outbreak of adverse reactions associated with contaminated heparin.

Authors:  David B Blossom; Alexander J Kallen; Priti R Patel; Alexis Elward; Luke Robinson; Ganpan Gao; Robert Langer; Kiran M Perkins; Jennifer L Jaeger; Katie M Kurkjian; Marilyn Jones; Sarah F Schillie; Nadine Shehab; Daniel Ketterer; Ganesh Venkataraman; Takashi Kei Kishimoto; Zachary Shriver; Ann W McMahon; K Frank Austen; Steven Kozlowski; Arjun Srinivasan; George Turabelidze; Carolyn V Gould; Matthew J Arduino; Ram Sasisekharan
Journal:  N Engl J Med       Date:  2008-12-03       Impact factor: 91.245

5.  Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4.

Authors:  D A Lane; J Denton; A M Flynn; L Thunberg; U Lindahl
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857

6.  Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.

Authors:  T E Warkentin; M N Levine; J Hirsh; P Horsewood; R S Roberts; M Gent; J G Kelton
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Review 7.  Standardization and clinical utility of thrombin-generation assays.

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Journal:  Semin Thromb Hemost       Date:  2008-12-15       Impact factor: 4.180

8.  Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity.

Authors:  J Choay; M Petitou; J C Lormeau; P Sinaÿ; B Casu; G Gatti
Journal:  Biochem Biophys Res Commun       Date:  1983-10-31       Impact factor: 3.575

9.  Glycosaminoglycan mimetic biomaterials. 4. Synthesis of sulfated lactose-based glycopolymers that exhibit anticoagulant activity.

Authors:  Xue-Long Sun; Daniel Grande; Subramanian Baskaran; Stephen R Hanson; Elliot L Chaikof
Journal:  Biomacromolecules       Date:  2002 Sep-Oct       Impact factor: 6.988

10.  Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.

Authors:  Wei Li; Daniel J D Johnson; Charles T Esmon; James A Huntington
Journal:  Nat Struct Mol Biol       Date:  2004-08-15       Impact factor: 15.369

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2.  Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan.

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3.  Influencing Early Stages of Neuromuscular Junction Formation through Glycocalyx Engineering.

Authors:  Mia L Huang; Ember M Tota; Taryn M Lucas; Kamil Godula
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4.  Glycosidase Inhibition by Multivalent Presentation of Heparan Sulfate Saccharides on Bottlebrush Polymers.

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5.  A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165).

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Review 6.  Tools for mammalian glycoscience research.

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7.  Heparan Sulfate Mimicking Glycopolymer Prevents Pancreatic β Cell Destruction and Suppresses Inflammatory Cytokine Expression in Islets under the Challenge of Upregulated Heparanase.

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8.  Design, synthesis, and evaluation of heparan sulfate mimicking glycopolymers for inhibiting heparanase activity.

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9.  Synthesis and anticoagulant activity of polyureas containing sulfated carbohydrates.

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Review 10.  Heparin-Mimicking Polymers: Synthesis and Biological Applications.

Authors:  Samantha J Paluck; Thi H Nguyen; Heather D Maynard
Journal:  Biomacromolecules       Date:  2016-10-14       Impact factor: 6.988

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