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Literature DB >> 2412292

Antigenic variation and resistance to neutralization in poliovirus type 1.

D C Diamond, B A Jameson, J Bonin, M Kohara, S Abe, H Itoh, T Komatsu, M Arita, S Kuge, A Nomoto.

Abstract

Mutations have been identified in variants of poliovirus, type 1 (Mahoney) on the basis of their resistance to neutralization by individual monoclonal antibodies. The phenotypes of these variants were defined in terms of antibody binding; the pattern of epitopes expressed or able to be exploited for neutralization were complex. Single amino acid changes can have distant (in terms of linear sequence) and generalized effects on the antigenic structure of poliovirus and similarly constituted virions.

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Year: 1985 PMID： 2412292 DOI： 10.1126/science.2412292

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

38 in total

1. Molecular basis of antigenic structures of poliovirus: implications for their evolution during morphogenesis.

Authors: K Wiegers; R Dernick
Journal: J Virol Date: 1992-07 Impact factor: 5.103

2. High frequency of single-base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus.

Authors: J C de la Torre; C Giachetti; B L Semler; J J Holland
Journal: Proc Natl Acad Sci U S A Date: 1992-04-01 Impact factor: 11.205

3. Molecular basis for linkage of a continuous and discontinuous neutralization epitope on the structural polypeptide VP2 of poliovirus type 1.

Authors: K J Wiegers; K Wetz; R Dernick
Journal: J Virol Date: 1990-03 Impact factor: 5.103

4. Use of a lambda gt11 expression library to localize a neutralizing antibody-binding site in glycoprotein E2 of Sindbis virus.

Authors: K S Wang; J H Strauss
Journal: J Virol Date: 1991-12 Impact factor: 5.103

5. Mutations conferring resistance to neutralization with monoclonal antibodies in type 1 poliovirus can be located outside or inside the antibody-binding site.

Authors: B Blondel; R Crainic; O Fichot; G Dufraisse; A Candrea; D Diamond; M Girard; F Horaud
Journal: J Virol Date: 1986-01 Impact factor: 5.103

10. Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique.

Authors: R Bassel-Duby; D R Spriggs; K L Tyler; B N Fields
Journal: J Virol Date: 1986-10 Impact factor: 5.103

Antigenic variation and resistance to neutralization in poliovirus type 1.

1. Molecular basis of antigenic structures of poliovirus: implications for their evolution during morphogenesis.

2. High frequency of single-base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus.

3. Molecular basis for linkage of a continuous and discontinuous neutralization epitope on the structural polypeptide VP2 of poliovirus type 1.

4. Use of a lambda gt11 expression library to localize a neutralizing antibody-binding site in glycoprotein E2 of Sindbis virus.

5. Mutations conferring resistance to neutralization with monoclonal antibodies in type 1 poliovirus can be located outside or inside the antibody-binding site.

6. Very high frequency of reversion to guanidine resistance in clonal pools of guanidine-dependent type 1 poliovirus.

7. Antigenic modification of polioviruses by host proteolytic enzymes.

8. DNA amplification-restricted transcription-translation: rapid analysis of rhesus rotavirus neutralization sites.

Review 9. The alphaviruses: gene expression, replication, and evolution.

10. Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique.