Literature DB >> 24122809

Organ preservation surgery for low- and intermediate-grade laryngeal chondrosarcomas: analysis of 16 cases.

Cesare Piazza1, Francesca Del Bon, Paola Grazioli, Stefano Mangili, Diego Barbieri, Piero Nicolai, Giorgio Peretti.   

Abstract

OBJECTIVES/HYPOTHESIS: To demonstrate that endoscopic resection (ER), open partial laryngectomies, and cricotracheal resection and anastomosis (CTRA) achieve a good balance between oncologic radicality and organ preservation for laryngeal low-grade chondrosarcoma (LCS) and intermediate-grade chondrosarcoma (ICS). STUDY
DESIGN: Retrospective series in an academic institution.
METHODS: Between 2001 and 2013, we treated 13 cricoid, two thyroid, and one arytenoid LCS and ICS. Two cricoid and the only arytenoid LCS were managed by ER. Two thyroid ala LCS were submitted to laminectomy. Five ICS and six LCS of the cricoid received CTRA.
RESULTS: Nine patients only required tracheotomy, removed after a maximum of 14 days. Three patients required a nasogastric feeding tube, removed after a maximum of 8 days. Immediate complications included one bleeding, one cervical emphysema, and one partial anastomotic dehiscence. The only late complication was anastomotic stenosis that was resolved by laser resection. All patients regained regular oral feeding and a voice ranging from normal to moderate dysphonia. At the last follow-up, two patients died of unrelated causes, seven are alive with asymptomatic and radiologically stable residual disease, and seven are alive without evidence of persistent disease. One patient received total laryngectomy 11 years after CTRA for recurrent symptomatic disease.
CONCLUSIONS: Organ preservation surgery for laryngeal LCS and ICS represents a treatment option with low morbidity, good quality of life, and fair possibility to obtain oncologic radicality. LEVEL OF EVIDENCE: 4.
© 2013 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Laryngeal chondrosarcoma; cricotracheal resection and anastomosis; endoscopic resection; open neck partial laryngectomy

Mesh:

Year:  2013        PMID: 24122809     DOI: 10.1002/lary.24416

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  4 in total

Review 1.  Chondrosarcomas of the head and neck.

Authors:  Andrés Coca-Pelaz; Juan P Rodrigo; Asterios Triantafyllou; Jennifer L Hunt; Juan C Fernández-Miranda; Primož Strojan; Remco de Bree; Alessandra Rinaldo; Robert P Takes; Alfio Ferlito
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-11-10       Impact factor: 2.503

2.  Surgical management and oncological outcome of non-squamous cell carcinoma of the larynx: a bicentric study.

Authors:  Andrea Iandelli; Francesco Missale; Cesare Piazza; Giorgio Peretti; Andrea Laborai; Marta Filauro; Filippo Marchi; Francesca Del Bon; Pietro Perotti; Giampiero Parrinello
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-09-24       Impact factor: 2.503

3.  Laryngeal chondrosarcoma, case report and literature review.

Authors:  Carlos Hernández-Brito; María Alejandra Salazar-Álvarez; Mario Enrique Álvarez-Bojórquez; Francisco Carlos Cisneros-Juvera; Javier López-Gómez; Ángel Elizalde-Méndez; Martín Granados-García
Journal:  Int J Surg Case Rep       Date:  2018-08-09

4.  Prognostic factors for laryngeal sarcoma and nomogram development for prediction: a retrospective study based on SEER database.

Authors:  Jia Gu; Zhifan Zuo; Lei Sun; Li Li; Ning Zhao
Journal:  Ann Transl Med       Date:  2020-04
  4 in total

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