Literature DB >> 24122342

The many lives of CTIP2: from AIDS to cancer and cardiac hypertrophy.

Valentin Le Douce1, Thomas Cherrier, Raphael Riclet, Olivier Rohr, Christian Schwartz.   

Abstract

CTIP2 is a key transcriptional regulator involved in numerous physiological functions. Initial works have shown the importance of CTIP2 in the establishment and persistence of HIV latency in microglial cells, the main latent/quiescent viral reservoir in the brain. Recent studies have highlighted the importance of CTIP2 in several other pathologies, such as cardiac hypertrophy and various types of human malignancies. Targeting CTIP2 may therefore constitute a new approach in the treatment of these pathologies.
© 2013 Wiley Periodicals, Inc.

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Year:  2014        PMID： 24122342     DOI： 10.1002/jcp.24490

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  11 in total

1.  Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4+ T-Cell Activation.

Authors:  Marion Dubuissez; Ingrid Loison; Sonia Paget; Han Vorng; Saliha Ait-Yahia; Olivier Rohr; Anne Tsicopoulos; Dominique Leprince
Journal:  Mol Cell Biol       Date:  2016-06-15       Impact factor: 4.272

Review 2.  Neural effects of inflammation, cardiovascular disease, and HIV: Parallel, perpendicular, or progressive?

Authors:  C L Nemeth; M Bekhbat; G N Neigh
Journal:  Neuroscience       Date:  2014-09-17       Impact factor: 3.590

Review 3.  HIV-1 latency in monocytes/macrophages.

Authors:  Amit Kumar; Wasim Abbas; Georges Herbein
Journal:  Viruses       Date:  2014-04-22       Impact factor: 5.048

Review 4.  Targeting the Brain Reservoirs: Toward an HIV Cure.

Authors:  Céline Marban; Faezeh Forouzanfar; Amina Ait-Ammar; Faiza Fahmi; Hala El Mekdad; Fadoua Daouad; Olivier Rohr; Christian Schwartz
Journal:  Front Immunol       Date:  2016-09-30       Impact factor: 7.561

5.  HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1.

Authors:  Valentin Le Douce; Faezeh Forouzanfar; Sebastian Eilebrecht; Benoit Van Driessche; Amina Ait-Ammar; Roxane Verdikt; Yoshihito Kurashige; Céline Marban; Virginie Gautier; Ermanno Candolfi; Arndt G Benecke; Carine Van Lint; Olivier Rohr; Christian Schwartz
Journal:  Sci Rep       Date:  2016-10-11       Impact factor: 4.379

Review 6.  Bcl11b-A Critical Neurodevelopmental Transcription Factor-Roles in Health and Disease.

Authors:  Matthew J Lennon; Simon P Jones; Michael D Lovelace; Gilles J Guillemin; Bruce J Brew
Journal:  Front Cell Neurosci       Date:  2017-03-29       Impact factor: 5.505

7.  HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing.

Authors:  F Forouzanfar; S Ali; C Wallet; M De Rovere; C Ducloy; H El Mekdad; M El Maassarani; A Aït-Ammar; J Van Assche; E Boutant; F Daouad; F Margottin-Goguet; C Moog; C Van Lint; C Schwartz; O Rohr
Journal:  Sci Rep       Date:  2019-09-11       Impact factor: 4.379

Review 8.  Microglial Cells: The Main HIV-1 Reservoir in the Brain.

Authors:  Clementine Wallet; Marco De Rovere; Jeanne Van Assche; Fadoua Daouad; Stéphane De Wit; Virginie Gautier; Patrick W G Mallon; Alessandro Marcello; Carine Van Lint; Olivier Rohr; Christian Schwartz
Journal:  Front Cell Infect Microbiol       Date:  2019-10-24       Impact factor: 5.293

9.  Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage.

Authors:  Amina Ait-Ammar; Maxime Bellefroid; Fadoua Daouad; Valérie Martinelli; Jeanne Van Assche; Clémentine Wallet; Anthony Rodari; Marco De Rovere; Birthe Fahrenkrog; Christian Schwartz; Carine Van Lint; Virginie Gautier; Olivier Rohr
Journal:  Sci Rep       Date:  2021-01-29       Impact factor: 4.379

Review 10.  Are BET Inhibitors yet Promising Latency-Reversing Agents for HIV-1 Reactivation in AIDS Therapy?

Authors:  Thanarat Salahong; Christian Schwartz; Rungroch Sungthong
Journal:  Viruses       Date:  2021-05-29       Impact factor: 5.048
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