BACKGROUND: The aim of this study was to investigate whether total atrial conduction time (TACT) assessed via tissue Doppler imaging (PA-TDI interval) can identify patients with early recurrent atrial fibrillation (ERAF) after successful direct-current electrical cardioversion (CV) of persistent atrial fibrillation (persPAF). METHODS AND RESULTS: A total of 54 patients without antiarrhythmic drug medication (mean ± SD: 66 ± 10.4 years; 33% women) with persPAF and successful CV were enrolled between May 2012 and May 2013. TACT was measured 6 hours after successful CV in the left atrium by tissue Doppler imaging (PA-TDI interval). ERAF was determined via Holter-electrocardiogram over a period of 7 days after CV. Receiver opearting characteristic analysis was used to determine an optimal cutoff value of PA-TDI interval for prognosis of ERAF. Based on this result, recurrence-free survival was assessed with Mantel-Haenszel's log-rank test. ERAF occurred in 23 patients (43%). PA-TDI interval was longer in patients with ERAF compared to those who maintained sinus rhythm (mean ± SD: 163.5 ± 11.1 vs 132.3 ± 11.2 milliseconds; P < 0.00001). At the cutoff value of 152 milliseconds, PA-TDI interval sensitivity and specificity related to ERAF were 87% and 100%, respectively. CONCLUSION: Measuring PA-TDI interval may help to predict ERAF after successful CV in patients with persAF.
BACKGROUND: The aim of this study was to investigate whether total atrial conduction time (TACT) assessed via tissue Doppler imaging (PA-TDI interval) can identify patients with early recurrent atrial fibrillation (ERAF) after successful direct-current electrical cardioversion (CV) of persistent atrial fibrillation (persPAF). METHODS AND RESULTS: A total of 54 patients without antiarrhythmic drug medication (mean ± SD: 66 ± 10.4 years; 33% women) with persPAF and successful CV were enrolled between May 2012 and May 2013. TACT was measured 6 hours after successful CV in the left atrium by tissue Doppler imaging (PA-TDI interval). ERAF was determined via Holter-electrocardiogram over a period of 7 days after CV. Receiver opearting characteristic analysis was used to determine an optimal cutoff value of PA-TDI interval for prognosis of ERAF. Based on this result, recurrence-free survival was assessed with Mantel-Haenszel's log-rank test. ERAF occurred in 23 patients (43%). PA-TDI interval was longer in patients with ERAF compared to those who maintained sinus rhythm (mean ± SD: 163.5 ± 11.1 vs 132.3 ± 11.2 milliseconds; P < 0.00001). At the cutoff value of 152 milliseconds, PA-TDI interval sensitivity and specificity related to ERAF were 87% and 100%, respectively. CONCLUSION: Measuring PA-TDI interval may help to predict ERAF after successful CV in patients with persAF.
Authors: Johannes W Dietrich; Patrick Müller; Fabian Schiedat; Markus Schlömicher; Justus Strauch; Apostolos Chatzitomaris; Harald H Klein; Andreas Mügge; Josef Köhrle; Eddy Rijntjes; Ina Lehmphul Journal: Eur Thyroid J Date: 2015-05-23
Authors: Jan-Thorben Sieweke; Saskia Biber; Karin Weissenborn; Peter U Heuschmann; Muharrem Akin; Florian Zauner; Maria M Gabriel; Ramona Schuppner; Dominik Berliner; Johann Bauersachs; Gerrit M Grosse; Udo Bavendiek Journal: Clin Res Cardiol Date: 2019-06-24 Impact factor: 5.460
Authors: Patrick Müller; Bob Weijs; Nadine M A A Bemelmans; Andreas Mügge; Lars Eckardt; Harry J G M Crijns; Jeroen J Bax; Dominik Linz; Dennis W den Uijl Journal: Clin Res Cardiol Date: 2021-08-28 Impact factor: 5.460
Authors: Johannes Steinhard; Andreas Entenmann; Elise van der Valk; Ralf Schmitz; Jörg Heinig; Kai Thorsten Laser; Miriam Michel Journal: PLoS One Date: 2018-07-02 Impact factor: 3.240