Emily L Falls 1 , Milan Milovancev , Geraldine B Hunt , Leticia Daniel , Margo L Mehl , Chad W Schmiedt . Show Affiliations »
Abstract
OBJECTIVE: To report long-term clinical outcome in dogs treated for single congenital extrahepatic portosystemic shunt (CEHPSS) with a ameroid ring constrictor (ARC) and to identify perioperative variables associated with outcome. STUDY DESIGN: Retrospective, multi-institutional study. ANIMALS: Dogs (n = 206) with CEHPSS. METHODS: Medical records of dogs with CEHPSS treated by ARC were reviewed for perioperative and short-term (<1 month) data. Long-term follow-up information was obtained by telephone interview with referring veterinarians and/or owners. Kaplan-Meier analysis was used to estimate median survival time. Factors associated with short-term survival, outcome grade, and total survival time were identified. RESULTS: Fifteen dogs died <1 month after ARC placement. Follow-up data were obtained for 112 of 191 dogs that survived >1 month; median follow was 54 months (range, 1-175 months) and 103 (92%) dogs had no clinical signs. Estimated median survival time was 152 months. Variables significantly associated with short-term survival included being intact and a low total white blood cell (WBC) count. Variables significantly associated with a successful outcome included having surgery later in the study period and negative postoperative nuclear scintigraphy. In the long-term survival analyses, intact dogs and those with higher WBC counts and occlusion pressures and lower bile acid concentrations were more likely to survive. CONCLUSIONS: Dogs with CEHPSS treated by ARC generally have a good prognosis and prolonged postoperative survival. © Copyright 2013 by The American College of Veterinary Surgeons.
OBJECTIVE: To report long-term clinical outcome in dogs treated for single congenital extrahepatic portosystemic shunt (CEHPSS) with a ameroid ring constrictor (ARC) and to identify perioperative variables associated with outcome. STUDY DESIGN: Retrospective, multi-institutional study. ANIMALS: Dogs (n = 206) with CEHPSS. METHODS: Medical records of dogs with CEHPSS treated by ARC were reviewed for perioperative and short-term (<1 month) data. Long-term follow-up information was obtained by telephone interview with referring veterinarians and/or owners. Kaplan-Meier analysis was used to estimate median survival time. Factors associated with short-term survival, outcome grade, and total survival time were identified. RESULTS: Fifteen dogs died <1 month after ARC placement. Follow-up data were obtained for 112 of 191 dogs that survived >1 month; median follow was 54 months (range, 1-175 months) and 103 (92%) dogs had no clinical signs. Estimated median survival time was 152 months. Variables significantly associated with short-term survival included being intact and a low total white blood cell (WBC) count. Variables significantly associated with a successful outcome included having surgery later in the study period and negative postoperative nuclear scintigraphy. In the long-term survival analyses, intact dogs and those with higher WBC counts and occlusion pressures and lower bile acid concentrations were more likely to survive. CONCLUSIONS: Dogs with CEHPSS treated by ARC generally have a good prognosis and prolonged postoperative survival. © Copyright 2013 by The American College of Veterinary Surgeons.
Entities: Chemical
Disease
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Year: 2013
PMID: 24118005 DOI: 10.1111/j.1532-950X.2013.12072.x
Source DB: PubMed Journal: Vet Surg ISSN: 0161-3499 Impact factor: 1.495