Literature DB >> 24117837

Cost-effectiveness of using Quantiferon Gold (QFT-G)® versus tuberculin skin test (TST) among U.S. and foreign born populations at a public health department clinic with a low prevalence of tuberculosis.

Ayesha Z Iqbal1, Jenelle Leighton, John Anthony, Richard C Knaup, Eleanor B Peters, Thomas C Bailey.   

Abstract

OBJECTIVE: The purpose of this study was to determine the cost benefit to routinely using QFT-G versus the standard TST for screening U.S. and foreign born populations at a public health department clinic with a low prevalence of tuberculosis. DESIGN AND SAMPLE: A comparative cost analysis of the monetization between QFT-G and TST was conducted: Data from the health department's Chest Clinic patients seen in 2007 were used to model cost predictions. MEASURES: The net costs of screening, x-rays, the standard 9 months of latent tuberculosis infection treatment, laboratory, and administration for U.S. born patients and foreign born patients were investigated.
RESULTS: There are no apparent cost savings for U.S. born individuals, but due to the higher specificity of QFT-G for foreign born BCG-vaccinated individuals, there are unnecessary expenditures associated with the higher number of false positives incurred when using TST compared with QFT-G on 1,000 foreign born individuals (69%, 18%).
CONCLUSION: QFT-G is cost-effective and should be used at local health department clinics that want to achieve savings in screening and treating those suspected of having TB infection, especially for high-risk populations such as foreign born individuals.
© 2013 Wiley Periodicals, Inc.

Entities:  

Keywords:  Cost-effectiveness; LTBI; TST; screening; tuberculosis

Mesh:

Year:  2013        PMID: 24117837     DOI: 10.1111/phn.12083

Source DB:  PubMed          Journal:  Public Health Nurs        ISSN: 0737-1209            Impact factor:   1.462


  7 in total

Review 1.  Defining a migrant-inclusive tuberculosis research agenda to end TB.

Authors:  P B Shete; D Boccia; P Dhavan; N Gebreselassie; K Lönnroth; S Marks; A Matteelli; D L Posey; M J van der Werf; C A Winston; C Lienhardt
Journal:  Int J Tuberc Lung Dis       Date:  2018-08-01       Impact factor: 2.373

Review 2.  A scoping review of cost-effectiveness of screening and treatment for latent tubercolosis infection in migrants from high-incidence countries.

Authors:  Lorenzo Zammarchi; Gianluigi Casadei; Marianne Strohmeyer; Filippo Bartalesi; Carola Liendo; Alberto Matteelli; Maurizio Bonati; Eduardo Gotuzzo; Alessandro Bartoloni
Journal:  BMC Health Serv Res       Date:  2015-09-24       Impact factor: 2.655

3.  Estimated Prevalence of Tuberculosis Infection Among a New York City Clinic Population Using Interferon-gamma Release Assays.

Authors:  Natalie L Stennis; Lisa Trieu; Shama D Ahuja; Tiffany G Harris
Journal:  Open Forum Infect Dis       Date:  2014-07-29       Impact factor: 3.835

4.  Resource implications of the latent tuberculosis cascade of care: a time and motion study in five countries.

Authors:  H Alsdurf; O Oxlade; M Adjobimey; F Ahmad Khan; M Bastos; N Bedingfield; A Benedetti; D Boafo; T N Buu; L Chiang; V Cook; D Fisher; G J Fox; F Fregonese; P Hadisoemarto; J C Johnston; F Kassa; R Long; S Moayedi Nia; T A Nguyen; J Obeng; C Paulsen; K Romanowski; R Ruslami; K Schwartzman; H Sohn; E Strumpf; A Trajman; C Valiquette; L Yaha; D Menzies
Journal:  BMC Health Serv Res       Date:  2020-04-21       Impact factor: 2.655

5.  Primary care providers' and nurses' knowledge, attitudes, and skills regarding latent TB infection testing and treatment: A qualitative study from Rhode Island.

Authors:  Daria Szkwarko; Steven Kim; E Jane Carter; Roberta E Goldman
Journal:  PLoS One       Date:  2022-04-15       Impact factor: 3.752

Review 6.  The impact of migration on tuberculosis epidemiology and control in high-income countries: a review.

Authors:  Manish Pareek; Christina Greenaway; Teymur Noori; Jose Munoz; Dominik Zenner
Journal:  BMC Med       Date:  2016-03-23       Impact factor: 8.775

7.  The effectiveness and cost-effectiveness of screening for latent tuberculosis among migrants in the EU/EEA: a systematic review.

Authors:  Christina Greenaway; Manish Pareek; Claire-Nour Abou Chakra; Moneeza Walji; Iuliia Makarenko; Balqis Alabdulkarim; Catherine Hogan; Ted McConnell; Brittany Scarfo; Robin Christensen; Anh Tran; Nick Rowbotham; Marieke J van der Werf; Teymur Noori; Kevin Pottie; Alberto Matteelli; Dominik Zenner; Rachael L Morton
Journal:  Euro Surveill       Date:  2018-04
  7 in total

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