Literature DB >> 24115091

Excised larynx evaluation of wedge-shaped adjustable balloon implant for minimally invasive type I thyroplasty.

Matthew R Hoffman1, Erin E Devine, Timothy M McCulloch, Jack J Jiang.   

Abstract

OBJECTIVES/HYPOTHESIS: To describe the method of inserting a wedge-shaped adjustable balloon implant (wABI) via a minithyrotomy for medialization thyroplasty and evaluate its effect on a range of phonatory parameters using the excised larynx bench apparatus. STUDY
DESIGN: Repeated measures with each larynx serving as its own control.
METHODS: A prototype wABI was deployed in six excised canine larynges of various sizes through a minithyrotomy and then filled with saline. Mucosal wave, aerodynamic, and acoustic parameters were measured for three conditions: normal, vocal fold paralysis, and paralysis with the wABI.
RESULTS: Phonation threshold pressure (P < .001), flow (P < .001), and power (P = .002) were significantly lower for wABI compared to paralysis trials; values did not differ significantly from normal trials. Percent jitter (P = .002) and percent shimmer (P = .007) were also significantly decreased compared to the paralysis condition, and values were not significantly different compared to normal. The mucosal wave was preserved after insertion of the wABI.
CONCLUSIONS: Effective vocal fold medialization with preservation of the mucosal wave was observed with the wABI in this preliminary excised larynx experiment. The wABI offers the potential for a minimally invasive insertion in addition to postoperative adjustability. Further studies in living animals and humans are warranted to evaluate clinical utility. LEVEL OF EVIDENCE: NA.
© 2013 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Adjustable balloon implant; glottic insufficiency; medialization thyroplasty; vocal fold paralysis

Mesh:

Year:  2013        PMID: 24115091      PMCID: PMC4235617          DOI: 10.1002/lary.24409

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


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