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Literature DB >> 2411047

Intermediate filaments of human trophoblast and choriocarcinoma cell lines.

Abstract

Human term placenta and two human choriocarcinoma cell lines were studied immunohistochemically and by immunoblotting with monoclonal antibodies to keratin polypeptides and vimentin. Four keratin polypeptides (40, 45, 52, 54 K) were detected in both normal and malignant trophoblastic cells. The presence of the 54 K keratin polypeptide distinguishes the benign and malignant trophoblastic cells from human embryonal carcinoma cells and a yolk sac carcinoma cell line.

Entities: Disease Gene Species

Mesh：

Substances：
Peptides
Vimentin
Keratins

Year: 1985 PMID： 2411047 DOI： 10.1007/bf00737077

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398

17 in total

1. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors: H Towbin; T Staehelin; J Gordon
Journal: Proc Natl Acad Sci U S A Date: 1979-09 Impact factor: 11.205

2. The establishment of a cell line of human hormone-synthesizing trophoblastic cells in vitro.

Authors: R A Pattillo; G O Gey
Journal: Cancer Res Date: 1968-07 Impact factor: 12.701

3. Differences of expression of cytoskeletal proteins in cultured rat hepatocytes and hepatoma cells.

Authors: W W Franke; D Mayer; E Schmid; H Denk; E Borenfreund
Journal: Exp Cell Res Date: 1981-08 Impact factor: 3.905

4. The differential diagnosis of testicular germ cell tumors in theory and practice. A critical analysis of two major systems of classifiction and review of 389 cases.

Authors: A R von Hochstetter; C E Hedinger
Journal: Virchows Arch A Pathol Anat Histol Date: 1982-08

5. Non-seminomatous germ cell tumors of the testis. Immunohistochemical localization and serum levels of human chorionic gonadotropin (HCG) and pregnancy-specific beta-1 glycoprotein (SP-1); value of SP-1 as a tumor marker.

Authors: A J Suurmeijer; H W De Bruijn; J W Oosterhuis; D T Sleyfer; H S Koops; G J Fleuren
Journal: Oncodev Biol Med Date: 1982

6. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.

Authors: P W Andrews; I Damjanov; D Simon; G S Banting; C Carlin; N C Dracopoli; J Føgh
Journal: Lab Invest Date: 1984-02 Impact factor: 5.662

7. Monoclonal antibody to keratin filaments, specific for glandular epithelia and their tumors. Use in surgical pathology.

Authors: F Ramaekers; A Huysmans; O Moesker; A Kant; P Jap; C Herman; P Vooijs
Journal: Lab Invest Date: 1983-09 Impact factor: 5.662

Intermediate filaments of human trophoblast and choriocarcinoma cell lines.

1. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

2. The establishment of a cell line of human hormone-synthesizing trophoblastic cells in vitro.

3. Differences of expression of cytoskeletal proteins in cultured rat hepatocytes and hepatoma cells.

4. The differential diagnosis of testicular germ cell tumors in theory and practice. A critical analysis of two major systems of classifiction and review of 389 cases.

5. Non-seminomatous germ cell tumors of the testis. Immunohistochemical localization and serum levels of human chorionic gonadotropin (HCG) and pregnancy-specific beta-1 glycoprotein (SP-1); value of SP-1 as a tumor marker.

6. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.

7. Monoclonal antibody to keratin filaments, specific for glandular epithelia and their tumors. Use in surgical pathology.

8. Complex cytokeratin polypeptide patterns observed in certain human carcinomas.

9. Specific keratins as molecular markers for neoplasms with a stratified epithelial origin.

10. Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies.

1. Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures.

2. Intermediate filament proteins in choroid plexus and ependyma and their tumors.

3. Synthesis of type I homotrimer collagen molecules by cultured human lung adenocarcinoma cells.

4. Cytoskeletal regulation of calcium-permeable cation channels in the human syncytiotrophoblast: role of gelsolin.

5. CK19 is a sensitive marker for yolk sac tumours of the testis.