Literature DB >> 24110200

A new tool for quantifying and characterizing asymmetry in bilaterally paired structures.

S M Rolfe, E D Camci, E Mercan, L G Shapiro, T C Cox.   

Abstract

This paper introduces a new tool to quantify and characterize asymmetry in bilaterally paired structures. This method uses deformable registration to produce a dense vector field describing the point correspondences between two images of bilaterally paired structures. The deformation vector field properties are clustered to detect and describe regions of relevant asymmetry. Three methods are provided to analyze the asymmetries: the global asymmetry score uses cluster features to quantify overall asymmetry, the local asymmetry score quantifies asymmetry in user-defined regions of interest, and the asymmetry similarity measure quantifies pairwise similarity of individual asymmetry. The scores and image distances generated by this tool are shown to correlate highly with asymmetry ratings assigned by an expert.

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Mesh:

Year:  2013        PMID: 24110200      PMCID: PMC3801450          DOI: 10.1109/EMBC.2013.6610013

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN: 1557-170X


  5 in total

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5.  A point-wise quantification of asymmetry using deformation fields: application to the study of the Crouzon mouse model.

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Journal:  Med Image Comput Comput Assist Interv       Date:  2007
  5 in total
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Journal:  Orthod Craniofac Res       Date:  2019-05       Impact factor: 1.826

2.  Automated Detection of 3D Landmarks for the Elimination of Non-Biological Variation in Geometric Morphometric Analyses.

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4.  Utility and limitations of animal models for the functional validation of human sequence variants.

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  4 in total

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