Literature DB >> 2410919

Actinomycin and DNA transcription.

H M Sobell.   

Abstract

Recent advances in understanding how actinomycin binds to DNA have suggested its mechanism of action. Actinomycin binds to a premelted DNA conformation present within the transcriptional complex. This immobilizes the complex, interfering with the elongation of growing RNA chains. The model has a number of implications for understanding RNA synthesis.

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Year:  1985        PMID： 2410919      PMCID： PMC390561          DOI： 10.1073/pnas.82.16.5328

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

1.  Basis of actinomycin action. I. DNA binding and inhibition of RNA-polymerase synthetic reactions by actinomycin.

Authors:  I H GOLDBERG; M RABINOWITZ; E REICH
Journal:  Proc Natl Acad Sci U S A       Date:  1962-12-15       Impact factor: 11.205

Review 2.  Visualization of RNA synthesis on chromosomes.

Authors:  O L Miller; B A Hamkalo
Journal:  Int Rev Cytol       Date:  1972

3.  How actinomycin binds to DNA.

Authors:  H M Sobell
Journal:  Sci Am       Date:  1974-08       Impact factor: 2.142

4.  Stereochemistry of actinomycin binding to DNA. II. Detailed molecular model of actinomycin-DNA complex and its implications.

Authors:  H M Sobell; S C Jain
Journal:  J Mol Biol       Date:  1972-07-14       Impact factor: 5.469

5.  Stereochemistry of actinomycin binding to DNA. I. Refinement and further structural details of the actinomycin-deoxyguanosine crystalline complex.

Authors:  S C Jain; H M Sobell
Journal:  J Mol Biol       Date:  1972-07-14       Impact factor: 5.469

6.  Initiation of chains by RNA polymerase and the effects of inhibitors studied by a direct filtration technique.

Authors:  A Sentenac; E J Simon; P Fromageot
Journal:  Biochim Biophys Acta       Date:  1968-07-23

7.  Discontinuous in vitro transcription of DNA.

Authors:  J L Darlix; P Fromageot
Journal:  Biochimie       Date:  1972       Impact factor: 4.079

8.  Stereochemistry of actinomycin--DNA binding.

Authors:  H M Sobell; S C Jain; T D Sakore; C E Nordman
Journal:  Nat New Biol       Date:  1971-06-16

Review 9.  Actinomycin and nucleic acid function.

Authors:  E Reich; I H Goldberg
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1964

10.  The nucleotide sequence of the lactose messenger ribonucleic acid transcribed from the UV5 promoter mutant of Escherichia coli.

Authors:  N M Maizels
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205
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  159 in total

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Journal:  Mol Cell Biol       Date:  2001-02       Impact factor: 4.272

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Authors:  Melanie Schmid; Ramon A Gonzalez; Thomas Dobner
Journal:  J Virol       Date:  2011-12-14       Impact factor: 5.103

3.  Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells.

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Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-29       Impact factor: 11.205

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Journal:  Protoplasma       Date:  2016-01-13       Impact factor: 3.356

5.  IGF2BP2 stabilized FBXL19-AS1 regulates the blood-tumour barrier permeability by negatively regulating ZNF765 by STAU1-mediated mRNA decay.

Authors:  Xiaobai Liu; Peiqi Wu; Rui Su; Yixue Xue; Chunqing Yang; Di Wang; Xuelei Ruan; Jian Zheng; Yang Yang; Zhen Li; Yunhui Liu
Journal:  RNA Biol       Date:  2020-07-25       Impact factor: 4.652

6.  Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene.

Authors:  James L Kalabus; Qiuying Cheng; Raqeeb G Jamil; Erin G Schuetz; Javier G Blanco
Journal:  Toxicol Lett       Date:  2012-04-15       Impact factor: 4.372

Review 7.  The role of protein synthesis in memory consolidation: progress amid decades of debate.

Authors:  Pepe J Hernandez; Ted Abel
Journal:  Neurobiol Learn Mem       Date:  2007-11-28       Impact factor: 2.877

8.  Chromatin dynamics is correlated with replication timing.

Authors:  Artem Pliss; Kishore Malyavantham; Sambit Bhattacharya; Michael Zeitz; Ronald Berezney
Journal:  Chromosoma       Date:  2009-03-19       Impact factor: 4.316

9.  Lipopolysaccharides up-regulate Kir6.1/SUR2B channel expression and enhance vascular KATP channel activity via NF-kappaB-dependent signaling.

Authors:  Weiwei Shi; Ningren Cui; Zhongying Wu; Yang Yang; Shuang Zhang; Hongyu Gai; Daling Zhu; Chun Jiang
Journal:  J Biol Chem       Date:  2009-12-03       Impact factor: 5.157

10.  Hypercapnia induced shifts in gill energy budgets of Antarctic notothenioids.

Authors:  Katrin Deigweiher; Timo Hirse; Christian Bock; Magnus Lucassen; Hans O Pörtner
Journal:  J Comp Physiol B       Date:  2009-10-16       Impact factor: 2.200
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