Literature DB >> 2410918

Assignment of the gene for human DNA polymerase alpha to the X chromosome.

T S Wang, B E Pearson, H A Suomalainen, T Mohandas, L J Shapiro, J Schröder, D Korn.   

Abstract

We have applied an assay based on a monoclonal antibody that discriminates the activity of human DNA polymerase alpha in rodent-human somatic cell hybrid clones to identify a single genetic locus that is both necessary and sufficient for the expression of DNA polymerase alpha. We have mapped this locus to the short arm of the human X chromosome, near the junction of bands Xp21.3 and Xp22.1, and demonstrated that it is not expressed from an inactive X chromosome.

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Year:  1985        PMID： 2410918      PMCID： PMC390549          DOI： 10.1073/pnas.82.16.5270

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  23 in total

1.  A rapid banding technique for human chromosomes.

Authors:  M Seabright
Journal:  Lancet       Date:  1971-10-30       Impact factor: 79.321

2.  Human hypoxanthine-guanine phosphoribosyltransferase. Purification and subunit structure.

Authors:  W J Arnold; W N Kelley
Journal:  J Biol Chem       Date:  1971-12-10       Impact factor: 5.157

3.  Mechanisms of giemsa banding of chromosomes. I. Giemsa-11 banding with azure and eosin.

Authors:  H E Wyandt; D G Wysham; S K Minden; R S Anderson; F Hecht
Journal:  Exp Cell Res       Date:  1976-10-01       Impact factor: 3.905

4.  Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure.

Authors:  F C Kafatos; C W Jones; A Efstratiadis
Journal:  Nucleic Acids Res       Date:  1979-11-24       Impact factor: 16.971

5.  Mouse/human T-cell hybrids rosetting with sheep erythrocytes.

Authors:  H A Suomalainen; R A Goldsby; B A Osborne; J Schröder
Journal:  Scand J Immunol       Date:  1980       Impact factor: 3.487

6.  Regional assignment of the steroid sulfatase-X-linked ichthyosis locus: implications for a noninactivated region on the short arm of human X chromosome.

Authors:  T Mohandas; L J Shapiro; R S Sparkes; M C Sparkes
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

7.  The cell surface antigen locus, MIC2X, escapes X-inactivation.

Authors:  P Goodfellow; B Pym; T Mohandas; L J Shapiro
Journal:  Am J Hum Genet       Date:  1984-07       Impact factor: 11.025

8.  Random X inactivation resulting in mosaic nullisomy of region Xp21.1----p21.3 associated with heterozygosity for ornithine transcarbamylase deficiency and for chronic granulomatous disease.

Authors:  U Francke
Journal:  Cytogenet Cell Genet       Date:  1984

9.  Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation.

Authors:  G S Pai; J A Sprenkle; T T Do; C E Mareni; B R Migeon
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

10.  Human ornithine transcarbamylase locus mapped to band Xp21.1 near the Duchenne muscular dystrophy locus.

Authors:  V Lindgren; B de Martinville; A L Horwich; L E Rosenberg; U Francke
Journal:  Science       Date:  1984-11-09       Impact factor: 47.728
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  9 in total

1.  Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene.

Authors:  D W Chung; J A Zhang; C K Tan; E W Davie; A G So; K M Downey
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

2.  Expression of genes from the human active and inactive X chromosomes.

Authors:  C J Brown; L Carrel; H F Willard
Journal:  Am J Hum Genet       Date:  1997-06       Impact factor: 11.025

3.  Aphidicolin-resistant mutator strains of mouse teratocarcinoma.

Authors:  S Aizawa; L A Loeb; G M Martin
Journal:  Mol Gen Genet       Date:  1987-06

4.  Sex chromosome evolution: platypus gene mapping suggests that part of the human X chromosome was originally autosomal.

Authors:  J M Watson; J A Spencer; A D Riggs; J A Graves
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

5.  Exchange of terminal portions of X- and Y-chromosomal short arms in human XY females.

Authors:  J Levilliers; B Quack; J Weissenbach; C Petit
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

6.  Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion.

Authors:  Yuan Liu; Rajendra Prasad; William A Beard; Esther W Hou; Julie K Horton; Cynthia T McMurray; Samuel H Wilson
Journal:  J Biol Chem       Date:  2009-08-11       Impact factor: 5.157

7.  The evolutionary conservation of DNA polymerase alpha.

Authors:  M A Miller; D Korn; T S Wang
Journal:  Nucleic Acids Res       Date:  1988-08-25       Impact factor: 16.971

8.  X chromosome inactivation of the human TIMP gene.

Authors:  C J Brown; A M Flenniken; B R Williams; H F Willard
Journal:  Nucleic Acids Res       Date:  1990-07-25       Impact factor: 16.971

9.  Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.

Authors:  S W Wong; A F Wahl; P M Yuan; N Arai; B E Pearson; K Arai; D Korn; M W Hunkapiller; T S Wang
Journal:  EMBO J       Date:  1988-01       Impact factor: 11.598
  9 in total

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