Literature DB >> 2410913

A blood stage antigen of Plasmodium falciparum shares determinants with the sporozoite coat protein.

R L Coppel, J M Favaloro, P E Crewther, T R Burkot, A E Bianco, H D Stahl, D J Kemp, R F Anders, G V Brown.   

Abstract

A cDNA clone expressing a Plasmodium falciparum blood-stage antigen in Escherichia coli was identified by colony immunoassay using immune human sera. Antibodies affinity-purified on extracts of this clone reacted with both asexual blood stages and sporozoites of P. falciparum, recognizing a Mr23,000 protein in the blood stages. The nucleotide sequence of the cDNA revealed a signal peptide and an internal hydrophobic sequence typical of transmembrane anchor sequences. Located 3' to the putative anchor are two tetramers, Asn-Ala-Asn-Pro and Asn-Ala-Asp-Pro, which are closely related to the repeats of the circumsporozoite protein of P. falciparum. The blood stage protein is conserved amongst several isolates of P. falciparum, and antibodies against it are common in the sera of individuals living in the area where the parasite is endemic.

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Year:  1985        PMID： 2410913      PMCID： PMC390511          DOI： 10.1073/pnas.82.15.5121

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  24 in total

1.  Immune sera recognize on erythrocytes Plasmodium falciparum antigen composed of repeated amino acid sequences.

Authors:  R L Coppel; A F Cowman; R F Anders; A E Bianco; R B Saint; K R Lingelbach; D J Kemp; G V Brown
Journal:  Nature       Date:  1984 Aug 30-Sep 5       Impact factor: 49.962

2.  Identification of Plasmodium falciparum-infected mosquitoes by a double antibody enzyme-linked immunosorbent assay.

Authors:  T R Burkot; J L Williams; I Schneider
Journal:  Am J Trop Med Hyg       Date:  1984-09       Impact factor: 2.345

3.  Human antisera detect a Plasmodium falciparum genomic clone encoding a nonapeptide repeat.

Authors:  M Koenen; A Scherf; O Mercereau; G Langsley; L Sibilli; P Dubois; L Pereira da Silva; B Müller-Hill
Journal:  Nature       Date:  1984 Sep 27-Oct 3       Impact factor: 49.962

4.  Evidence for immunological cross-reaction between sporozoites and blood stages of a human malaria parasite.

Authors:  I A Hope; R Hall; D L Simmons; J E Hyde; J G Scaife
Journal:  Nature       Date:  1984 Mar 8-14       Impact factor: 49.962

5.  Conserved sequences flank variable tandem repeats in two S-antigen genes of Plasmodium falciparum.

Authors:  A F Cowman; R B Saint; R L Coppel; G V Brown; R F Anders; D J Kemp
Journal:  Cell       Date:  1985-04       Impact factor: 41.582

6.  Interspersed blocks of repetitive and charged amino acids in a dominant immunogen of Plasmodium falciparum.

Authors:  H D Stahl; P E Crewther; R F Anders; G V Brown; R L Coppel; A E Bianco; G F Mitchell; D J Kemp
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

7.  Antigens of the erythrocytes stages of the human malaria parasite Plasmodium falciparum detected by monoclonal antibodies.

Authors:  R Hall; J McBride; G Morgan; A Tait; J W Zolg; D Walliker; J Scaife
Journal:  Mol Biochem Parasitol       Date:  1983-03       Impact factor: 1.759

8.  Expression of Plasmodium falciparum blood-stage antigens in Escherichia coli: detection with antibodies from immune humans.

Authors:  D J Kemp; R L Coppel; A F Cowman; R B Saint; G V Brown; R F Anders
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

9.  Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum.

Authors:  J B Dame; J L Williams; T F McCutchan; J L Weber; R A Wirtz; W T Hockmeyer; W L Maloy; J D Haynes; I Schneider; D Roberts
Journal:  Science       Date:  1984-08-10       Impact factor: 47.728

10.  DNA cloning of Plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitope.

Authors:  V Enea; J Ellis; F Zavala; D E Arnot; A Asavanich; A Masuda; I Quakyi; R S Nussenzweig
Journal:  Science       Date:  1984-08-10       Impact factor: 47.728
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  16 in total

Review 1.  Class I HLA-restricted cytotoxic T lymphocyte responses against malaria--elucidation on the basis of HLA peptide binding motifs.

Authors:  D L Doolan; B Wizel; S L Hoffman
Journal:  Immunol Res       Date:  1996       Impact factor: 2.829

2.  An asparagine-rich protein from blood stages of Plasmodium falciparum shares determinants with sporozoites.

Authors:  H D Stahl; A E Bianco; P E Crewther; T Burkot; R L Coppel; G V Brown; R F Anders; D J Kemp
Journal:  Nucleic Acids Res       Date:  1986-04-11       Impact factor: 16.971

3.  Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

Authors:  M F Good; D Pombo; I A Quakyi; E M Riley; R A Houghten; A Menon; D W Alling; J A Berzofsky; L H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

4.  Plasmodium chabaudi antigen Pch105, Plasmodium falciparum antigen Pf155, and erythrocyte band 3 share cross-reactive epitopes.

Authors:  G Holmquist; R Udomsangpetch; K Berzins; H Wigzell; P Perlmann
Journal:  Infect Immun       Date:  1988-06       Impact factor: 3.441

5.  Molecular karyotype of Plasmodium falciparum: conserved linkage groups and expendable histidine-rich protein genes.

Authors:  D J Kemp; J K Thompson; D Walliker; L M Corcoran
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

6.  Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development.

Authors:  Cláudia Sá E Cunha; Britta Nyboer; Kirsten Heiss; Margarida Sanches-Vaz; Diana Fontinha; Ellen Wiedtke; Dirk Grimm; Jude Marek Przyborski; Maria M Mota; Miguel Prudêncio; Ann-Kristin Mueller
Journal:  Proc Natl Acad Sci U S A       Date:  2017-01-30       Impact factor: 11.205

7.  Stage-specific and species-specific antigens of Plasmodium vivax and Plasmodium ovale defined by monoclonal antibodies.

Authors:  P M Andrysiak; W E Collins; G H Campbell
Journal:  Infect Immun       Date:  1986-12       Impact factor: 3.441

8.  Differential antibody responses to Plasmodium falciparum and P. vivax circumsporozoite proteins in a human population.

Authors:  T R Burkot; P M Graves; R A Wirtz; B J Brabin; D Battistutta; J A Cattani; R M Maizels; M P Alpers
Journal:  J Clin Microbiol       Date:  1989-06       Impact factor: 5.948

9.  Identification of two integral membrane proteins of Plasmodium falciparum.

Authors:  J A Smythe; R L Coppel; G V Brown; R Ramasamy; D J Kemp; R F Anders
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

10.  Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola.

Authors:  Paula Figueiredo; Carla Benchimol; Dinora Lopes; Luís Bernardino; Virgílio E do Rosário; Luís Varandas; Fátima Nogueira
Journal:  Malar J       Date:  2008-11-17       Impact factor: 2.979
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