Literature DB >> 2410899

Pleomorphic T-cell leukaemia in a Caucasian adult: clinical phenotypic and functional characteristics.

C J Hawkey, A C Campbell, G A Bird, D I Gozzard, R A Robins, P J Toghill.   

Abstract

Pleomorphic T-cell leukaemia occurring in an adult Caucasian patient is described. The leukaemia cells expressed both antigenic determinants (T4 and T8) normally detected separately on either helper or suppressor cells. They functioned as helper cells and there was evidence of unbridled antibody production. It is possible that a distinctive subtype of pleomorphic T-cell leukaemia occurs in Caucasian patients.

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Year:  1985        PMID: 2410899      PMCID: PMC2418272          DOI: 10.1136/pgmj.61.715.457

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  11 in total

1.  Adult T-cell leukemia: clinical and hematologic features of 16 cases.

Authors:  T Uchiyama; J Yodoi; K Sagawa; K Takatsuki; H Uchino
Journal:  Blood       Date:  1977-09       Impact factor: 22.113

2.  Adult T-cell leukemia-lymphoma with unusual phenotype.

Authors:  B Schnitzer; E J Lovett; J L Hudson; K D McClatchey; D F Keren; L Dabich; B F Mitchell
Journal:  Lancet       Date:  1982-12-04       Impact factor: 79.321

3.  T cell chronic lymphocytic leukaemia with suppressor phenotype.

Authors:  F M Hofman; D Smith; W Hocking
Journal:  Clin Exp Immunol       Date:  1982-08       Impact factor: 4.330

4.  Antibodies in human sera reactive against an internal structural protein of human T-cell lymphoma virus.

Authors:  V S Kalyanaraman; M G Sarngadharan; P A Bunn; J D Minna; R C Gallo
Journal:  Nature       Date:  1981-11-19       Impact factor: 49.962

5.  Phenotypic and functional analysis of leukemic cells from 16 patients with adult T-cell leukemia/lymphoma.

Authors:  Y Yamada
Journal:  Blood       Date:  1983-01       Impact factor: 22.113

6.  The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus group.

Authors:  M Popovic; M S Reitz; M G Sarngadharan; M Robert-Guroff; V S Kalyanaraman; Y Nakao; I Miyoshi; J Minowada; M Yoshida; Y Ito; R C Gallo
Journal:  Nature       Date:  1982-11-04       Impact factor: 49.962

Review 7.  The differentiation and function of human T lymphocytes.

Authors:  E L Reinherz; S F Schlossman
Journal:  Cell       Date:  1980-04       Impact factor: 41.582

8.  Natural antibodies to the structural core protein (p24) of the human T-cell leukemia (lymphoma) retrovirus found in sera of leukemia patients in Japan.

Authors:  V S Kalyanaraman; M G Sarngadharan; Y Nakao; Y Ito; T Aoki; R C Gallo
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

9.  Phenotypic characterization of cutaneous T-cell lymphoma. Use of monoclonal antibodies to compare with other malignant T cells.

Authors:  B F Haynes; R S Metzgar; J D Minna; P A Bunn
Journal:  N Engl J Med       Date:  1981-05-28       Impact factor: 91.245

10.  Surface antigens on malignant Sézary and T-CLL cells correspond to those of mature T cells.

Authors:  L Boumsell; A Bernard; E L Reinherz; L M Nadler; J Ritz; H Coppin; Y Richard; L Dubertret; F Valensi; L Degos; J Lemerle; G Flandrin; J Dausset; S F Schlossman
Journal:  Blood       Date:  1981-03       Impact factor: 22.113

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