Literature DB >> 24107775

A new PERKspective on neurodegeneration.

Wiep Scheper1, Jeroen J M Hoozemans.   

Abstract

Targeting stress-induced kinases that regulate protein synthesis may be a new therapeutic strategy for treating neurodegenerative diseases.

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Year:  2013        PMID： 24107775     DOI： 10.1126/scitranslmed.3007641

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  9 in total

Review 1.  The eIF2-alpha kinase HRI: a potential target beyond the red blood cell.

Authors:  Nicholas Burwick; Bertal H Aktas
Journal:  Expert Opin Ther Targets       Date:  2017-10-30       Impact factor: 6.902

2.  Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms.

Authors:  Aric Flint Logsdon; Ryan Coddington Turner; Brandon Peter Lucke-Wold; Matthew James Robson; Zachary James Naser; Kelly Elizabeth Smith; Rae Reiko Matsumoto; Jason Delwyn Huber; Charles Lee Rosen
Journal:  Front Cell Neurosci       Date:  2014-12-10       Impact factor: 5.505

3.  Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.

Authors:  Martin Larhammar; Sarah Huntwork-Rodriguez; Zhiyu Jiang; Hilda Solanoy; Arundhati Sengupta Ghosh; Bei Wang; Joshua S Kaminker; Kevin Huang; Jeffrey Eastham-Anderson; Michael Siu; Zora Modrusan; Madeline M Farley; Marc Tessier-Lavigne; Joseph W Lewcock; Trent A Watkins
Journal:  Elife       Date:  2017-04-25       Impact factor: 8.140

4.  The unfolded protein response is activated in the olfactory system in Alzheimer's disease.

Authors:  Helen C Murray; Birger Victor Dieriks; Molly E V Swanson; Praju Vikas Anekal; Clinton Turner; Richard L M Faull; Leonardo Belluscio; Alan Koretsky; Maurice A Curtis
Journal:  Acta Neuropathol Commun       Date:  2020-07-14       Impact factor: 7.801

5.  Model Identifies Genetic Predisposition of Alzheimer's Disease as Key Decider in Cell Susceptibility to Stress.

Authors:  Ioanna C Stefani; François-Xavier Blaudin de Thé; Cleo Kontoravdi; Karen M Polizzi
Journal:  Int J Mol Sci       Date:  2021-11-05       Impact factor: 5.923

Review 6.  The unfolded protein response in neurodegenerative diseases: a neuropathological perspective.

Authors:  Wiep Scheper; Jeroen J M Hoozemans
Journal:  Acta Neuropathol       Date:  2015-07-26       Impact factor: 17.088

7.  The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress.

Authors:  J M van der Harg; A Nölle; R Zwart; A S Boerema; E S van Haastert; A M Strijkstra; J Jm Hoozemans; W Scheper
Journal:  Cell Death Dis       Date:  2014-08-28       Impact factor: 8.469

8.  PERK Pathway Activation Promotes Intracerebral Hemorrhage Induced Secondary Brain Injury by Inducing Neuronal Apoptosis Both in Vivo and in Vitro.

Authors:  Chengjie Meng; Juyi Zhang; Baoqi Dang; Haiying Li; Haitao Shen; Xiang Li; Zhong Wang
Journal:  Front Neurosci       Date:  2018-02-28       Impact factor: 4.677

Review 9.  Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

Authors:  Christopher P Webster; Emma F Smith; Pamela J Shaw; Kurt J De Vos
Journal:  Front Mol Neurosci       Date:  2017-05-02       Impact factor: 5.639
  9 in total

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