Literature DB >> 24106820

AA amyloidosis in a polyarteritis nodosa patient treated with tocilizumab.

Alojzija Hočevar1, Boris Lestan, Snežna Sodin Šemrl, Katja Lakota, Nika Kojc, Nataša Potočnik, Matija Tomšič.   

Abstract

Amyloid A (AA) (secondary) amyloidosis represents a severe complication of chronic inflammatory diseases. Since pathogenic mechanisms point to the central role of interleukin 6 (IL-6) in the process of amyloid AA generation, IL-6 blockade seems an attractive therapeutic option. We report a case of a patient with polyarteritis nodosa complicated by AA amyloidosis treated with tocilizumab.

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Year:  2013        PMID: 24106820     DOI: 10.3109/13506129.2013.838947

Source DB:  PubMed          Journal:  Amyloid        ISSN: 1350-6129            Impact factor:   7.141


  5 in total

Review 1.  Tocilizumab treatment in refractory polyarteritis nodosa: a case report and review of the literature.

Authors:  Martin Krusche; Nikolas Ruffer; Ina Kötter
Journal:  Rheumatol Int       Date:  2018-11-21       Impact factor: 2.631

2.  Treatment of polyarteritis nodosa with tocilizumab: a new therapeutic approach?

Authors:  Aurélie Saunier; Nahéma Issa; Marie-Anne Vandenhende; Philippe Morlat; Marie-Sylvie Doutre; Fabrice Bonnet
Journal:  RMD Open       Date:  2017-06-29

Review 3.  A young girl with severe polyarteritis nodosa successfully treated with tocilizumab: a case report.

Authors:  Margaux Boistault; Mireia Lopez Corbeto; Ariadna Carsi Durall; Florence A Aeschlimann; Pierre Quartier; Laura Berbel Arcobé
Journal:  Pediatr Rheumatol Online J       Date:  2021-12-03       Impact factor: 3.054

Review 4.  Serum Amyloid A Protein-Associated Kidney Disease: Presentation, Diagnosis, and Management.

Authors:  Jordan Thorne; David Clark; Laurette Geldenhuys; Keigan More; Amanda Vinson; Karthik Tennankore
Journal:  Kidney Med       Date:  2022-06-26

5.  Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.

Authors:  Tadeja Kuret; Katja Lakota; Polonca Mali; Saša Čučnik; Sonja Praprotnik; Matija Tomšič; Snezna Sodin-Semrl
Journal:  PLoS One       Date:  2018-04-04       Impact factor: 3.240

  5 in total

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