Literature DB >> 24106343

Hippo gains weight: added insights and complexity to pathway control.

Leonie Enderle1, Helen McNeill.   

Abstract

The Hippo pathway is a kinase cascade, formed by Hippo, Salvador, Warts, and Mats, that regulates the subcellular distribution and transcriptional activity of Yorkie. Yorkie is a transcriptional coactivator that promotes the expression of genes that inhibit apoptosis and drive cell proliferation. We review recent studies indicating that activity of the Hippo pathway is controlled by cell-cell junctions, cell adhesion molecules, scaffolding proteins, and cytoskeletal proteins, as well as by regulators of apical-basal polarity and extracellular tension.

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Year:  2013        PMID： 24106343     DOI： 10.1126/scisignal.2004208

Source DB:  PubMed          Journal:  Sci Signal        ISSN： 1945-0877            Impact factor:   8.192


  38 in total

Review 1.  Control of organ growth by patterning and hippo signaling in Drosophila.

Authors:  Kenneth D Irvine; Kieran F Harvey
Journal:  Cold Spring Harb Perspect Biol       Date:  2015-06-01       Impact factor: 10.005

Review 2.  Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.

Authors:  A R M Ruhul Amin; Phillip A Karpowicz; Thomas E Carey; Jack Arbiser; Rita Nahta; Zhuo G Chen; Jin-Tang Dong; Omer Kucuk; Gazala N Khan; Gloria S Huang; Shijun Mi; Ho-Young Lee; Joerg Reichrath; Kanya Honoki; Alexandros G Georgakilas; Amedeo Amedei; Amr Amin; Bill Helferich; Chandra S Boosani; Maria Rosa Ciriolo; Sophie Chen; Sulma I Mohammed; Asfar S Azmi; W Nicol Keith; Dipita Bhakta; Dorota Halicka; Elena Niccolai; Hiromasa Fujii; Katia Aquilano; S Salman Ashraf; Somaira Nowsheen; Xujuan Yang; Alan Bilsland; Dong M Shin
Journal:  Semin Cancer Biol       Date:  2015-03-06       Impact factor: 15.707

Review 3.  Hippo-yap signaling in ocular development and disease.

Authors:  Matthew Lee; Navneet Goraya; Seonhee Kim; Seo-Hee Cho
Journal:  Dev Dyn       Date:  2018-04-23       Impact factor: 3.780

4.  Validating upstream regulators of Yorkie activity in Hippo signaling through scalloped-based genetic epistasis.

Authors:  Jianzhong Yu; Duojia Pan
Journal:  Development       Date:  2018-02-21       Impact factor: 6.868

Review 5.  Big roles for Fat cadherins.

Authors:  Seth Blair; Helen McNeill
Journal:  Curr Opin Cell Biol       Date:  2017-12-16       Impact factor: 8.382

6.  The Hippo Pathway Is Essential for Maintenance of Apicobasal Polarity in the Growing Intestine of Caenorhabditis elegans.

Authors:  Hanee Lee; Junsu Kang; Soungyub Ahn; Junho Lee
Journal:  Genetics       Date:  2019-07-29       Impact factor: 4.562

7.  Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation.

Authors:  Helen McNeill; Antoine Reginensi
Journal:  J Am Soc Nephrol       Date:  2016-09-19       Impact factor: 10.121

8.  Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded.

Authors:  Ting Su; Michael Z Ludwig; Jiajie Xu; Richard G Fehon
Journal:  Dev Cell       Date:  2017-03-13       Impact factor: 12.270

9.  POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation.

Authors:  Xianjue Ma; Xiaowei Guo; Helena E Richardson; Tian Xu; Lei Xue
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-12       Impact factor: 11.205

10.  NOS1AP Functionally Associates with YAP To Regulate Hippo Signaling.

Authors:  Leanne Clattenburg; Michael Wigerius; Jiansong Qi; Jan K Rainey; Jillian L Rourke; Shanmugam Muruganandan; Christopher J Sinal; James P Fawcett
Journal:  Mol Cell Biol       Date:  2015-04-27       Impact factor: 4.272
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