Literature DB >> 2410515

A radioimmunoassay for thymosin alpha 1 that detects the native polypeptide, prothymosin alpha.

A A Haritos, B L Horecker.   

Abstract

A radioimmunoassay, developed for thymosin alpha 1, can also be utilized for the quantitation of the intact native polypeptide, prothymosin alpha, which contains the thymosin alpha 1 sequence at its NH2-terminus (Haritos et al., 1984a). The major epitope was characterized and found to include residues 1-10 at the NH2-terminus of thymosin alpha 1. As little as 5 pmol of prothymosin alpha can be detected in tissue extracts with this radioimmunoassay.

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Year:  1985        PMID： 2410515     DOI： 10.1016/0022-1759(85)90204-2

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  8 in total

1.  Expression of alpha-thymosins in human tissues in normal and abnormal growth.

Authors:  O E Tsitsiloni; J Stiakakis; A Koutselinis; J Gogas; C Markopoulos; P Yialouris; S Bekris; D Panoussopoulos; V Kiortsis; W Voelter
Journal:  Proc Natl Acad Sci U S A       Date:  1993-10-15       Impact factor: 11.205

2.  Prothymosin alpha in human blood.

Authors:  C Panneerselvam; A A Haritos; J Caldarella; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

3.  Do products of the myc proto-oncogene play a role in transcriptional regulation of the prothymosin alpha gene?

Authors:  P C Mol; R H Wang; D W Batey; L A Lee; C V Dang; S L Berger
Journal:  Mol Cell Biol       Date:  1995-12       Impact factor: 4.272

4.  Isolation and partial sequence of goat spleen prothymosin alpha.

Authors:  S Frillingos; M Frangou-Lazaridis; K Seferiadis; J D Hulmes; Y C Pan; O Tsolas
Journal:  Mol Cell Biochem       Date:  1991-11-13       Impact factor: 3.396

5.  Prothymosin alpha antisense oligomers inhibit myeloma cell division.

Authors:  A R Sburlati; R E Manrow; S L Berger
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

6.  The primary structure of rat parathymosin.

Authors:  T Komiyama; L X Pan; A A Haritos; J W Wideman; Y C Pan; M Chang; I Rogers; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

7.  Development of a specific IgY-based ELISA for prothymosin alpha, a bioactive polypeptide with diagnostic and therapeutic potential.

Authors:  Chrysoula-Evangelia Karachaliou; Ioannis V Kostopoulos; Vyronia Vassilakopoulou; Persefoni Klimentzou; Maria Paravatou-Petsotas; Wolfgang Voelter; Hubert Kalbacher; Christos Zikos; Ourania Tsitsilonis; Evangelia Livaniou
Journal:  Heliyon       Date:  2019-11-01

Review 8.  Prothymosin Alpha and Immune Responses: Are We Close to Potential Clinical Applications?

Authors:  P Samara; K Ioannou; O E Tsitsilonis
Journal:  Vitam Horm       Date:  2016-05-27       Impact factor: 3.421
  8 in total

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