Literature DB >> 24104540

Protein tyrosine phosphatase PTP1B in cell adhesion and migration.

Carlos O Arregui1, Ángela González1, Juan E Burdisso1, Ana E González Wusener1.   

Abstract

Cell migration requires a highly coordinated interplay between specialized plasma membrane adhesion complexes and the cytoskeleton. Protein phosphorylation/dephosphorylation modifications regulate many aspects of the integrin-cytoskeleton interdependence, including their coupling, dynamics, and organization to support cell movement. The endoplasmic reticulum-bound protein tyrosine phosphatase PTP1B has been implicated as a regulator of cell adhesion and migration. Recent results from our laboratory shed light on potential mechanisms, such as Src/FAK signaling through Rho GTPases and integrin-cytoskeletal coupling.

Entities:  

Keywords:  PTP1B; Src; adhesions; cytoskeleton; endoplasmic reticulum; integrins; migration; α-actinin

Mesh：

Substances：

Year:  2013        PMID： 24104540      PMCID： PMC3903686          DOI： 10.4161/cam.26375

Source DB:  PubMed          Journal:  Cell Adh Migr        ISSN： 1933-6918            Impact factor:   3.405


  63 in total

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Authors:  Kris A DeMali; Keith Burridge
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3.  PTP1B promotes focal complex maturation, lamellar persistence and directional migration.

Authors:  Juan E Burdisso; Ángela González; Carlos O Arregui
Journal:  J Cell Sci       Date:  2013-02-26       Impact factor: 5.285

4.  Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblasts.

Authors:  Deirdre A Buckley; Alan Cheng; Patrick A Kiely; Michel L Tremblay; Rosemary O'Connor
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

5.  The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase.

Authors:  G Izaguirre; L Aguirre; Y P Hu; H Y Lee; D D Schlaepfer; B J Aneskievich; B Haimovich
Journal:  J Biol Chem       Date:  2001-05-21       Impact factor: 5.157

6.  Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines.

Authors:  J D Bjorge; A Pang; D J Fujita
Journal:  J Biol Chem       Date:  2000-12-29       Impact factor: 5.157

7.  Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum.

Authors:  Fawaz G Haj; Peter J Verveer; Anthony Squire; Benjamin G Neel; Philippe I H Bastiaens
Journal:  Science       Date:  2002-03-01       Impact factor: 47.728

8.  Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.

Authors:  A Cheng; G S Bal; B P Kennedy; M L Tremblay
Journal:  J Biol Chem       Date:  2001-05-09       Impact factor: 5.157

9.  Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts.

Authors:  Louie Lamorte; Sonia Rodrigues; Veena Sangwan; Christopher E Turner; Morag Park
Journal:  Mol Biol Cell       Date:  2003-04-04       Impact factor: 4.138

10.  Tyrosine phosphorylation of the CrkII adaptor protein modulates cell migration.

Authors:  Takahisa Takino; Masahito Tamura; Hisashi Miyamori; Masaru Araki; Kazue Matsumoto; Hiroshi Sato; Kenneth M Yamada
Journal:  J Cell Sci       Date:  2003-06-10       Impact factor: 5.285
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  9 in total

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Journal:  J Cancer Res Clin Oncol       Date:  2014-11-06       Impact factor: 4.553

2.  PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway.

Authors:  Yuan Wang; Feng Yan; Qing Ye; Xiao Wu; Fan Jiang
Journal:  Sci Rep       Date:  2016-04-07       Impact factor: 4.379

3.  Phosphorylation inhibition of protein-tyrosine phosphatase 1B tyrosine-152 induces bone regeneration coupled with angiogenesis for bone tissue engineering.

Authors:  Yong Tang; Keyu Luo; Yin Chen; Yueqi Chen; Rui Zhou; Can Chen; Jiulin Tan; Moyuan Deng; Qijie Dai; Xueke Yu; Jian Liu; Chengmin Zhang; Wenjie Wu; Jianzhong Xu; Shiwu Dong; Fei Luo
Journal:  Bioact Mater       Date:  2021-01-07

4.  ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain.

Authors:  Shyam K More; Qinggang Wang; Emilie E Vomhof-DeKrey; James E Porter; Marc D Basson
Journal:  Pharmacol Res Perspect       Date:  2021-04

Review 5.  Targeting Breast Cancer and Their Stem Cell Population through AMPK Activation: Novel Insights.

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6.  ROCK Inhibitor (Y-27632) Abolishes the Negative Impacts of miR-155 in the Endometrium-Derived Extracellular Vesicles and Supports Embryo Attachment.

Authors:  Islam M Saadeldin; Bereket Molla Tanga; Seonggyu Bang; Chaerim Seo; Okjae Koo; Sung Ho Yun; Seung Il Kim; Sanghoon Lee; Jongki Cho
Journal:  Cells       Date:  2022-10-10       Impact factor: 7.666

Review 7.  Mammalian phospholipase D: Function, and therapeutics.

Authors:  M I McDermott; Y Wang; M J O Wakelam; V A Bankaitis
Journal:  Prog Lipid Res       Date:  2019-12-09       Impact factor: 16.195

8.  Phosphoproteome profiling of the macrophage response to different toll-like receptor ligands identifies differences in global phosphorylation dynamics.

Authors:  Virginie Sjoelund; Margery Smelkinson; Aleksandra Nita-Lazar
Journal:  J Proteome Res       Date:  2014-06-18       Impact factor: 4.466

9.  PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.

Authors:  Ana E González Wusener; Ángela González; Fumihiko Nakamura; Carlos O Arregui
Journal:  Biol Open       Date:  2015-12-23       Impact factor: 2.422
  9 in total

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