Klára Fekete1, Szabolcs Szatmári2, Ildikó Szőcs3, Csilla Szekeres3, József Szász2, László Mihálka4, Volodymyr Smolanka5, László Kardos6, László Csiba1, Dániel Bereczki7. 1. Department of Neurology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. 2. Department of Neurology, Clinical County Emergency Hospital, Târgu Mures, Romania; Department of Neurology, University of Medicine and Pharmacy, Târgu Mures, Romania. 3. Department of Neurology, Clinical County Emergency Hospital, Târgu Mures, Romania. 4. Department of Neurology and Toxicology, B.A.Z. County Hospital, Miskolc, Hungary. 5. Department of Neurology and Neurosurgery, University of Uzhgorod, Uzhgorod, Ukraine. 6. Infection Control Unit, Kenézy Hospital, Debrecen, Hungary. 7. Department of Neurology, Semmelweis University, Budapest, Hungary. Electronic address: bereczki@neur.sote.hu.
Abstract
BACKGROUND: Heavy alcohol consumption and smoking are known risk factors for stroke, but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital, and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. METHODS: Initial stroke severity was scored by the National Institutes of Health Stroke Scale. Case fatality and the modified outcome scale of the First International Stroke Trial were used to assess outcome. We used multiple regression analysis. RESULTS: Before their stroke, 24.5% were smokers and 24.7% admitted regular alcohol consumption. Neither smoking nor alcohol consumption status was associated with initial stroke severity. Case fatalities at discharge, at 30 days, and at 1 year were 12.2%, 16.9%, and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and nonconsumers in 30-day and in 1-year case fatality in all stroke patients and in ischemic stroke patients. In hemorrhagic stroke, there was a nonsignificant tendency for higher case fatality among alcohol consumers (39.5% versus 26.4%, P > .2, at 30 days and 48.8% versus 35.8%, P > .2, at 1 year). Smoking did not influence significantly the outcome at 30 days and at 1 year. CONCLUSION: Despite being risk factors, prestroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long-term outcome.
BACKGROUND: Heavy alcohol consumption and smoking are known risk factors for stroke, but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital, and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. METHODS: Initial stroke severity was scored by the National Institutes of Health Stroke Scale. Case fatality and the modified outcome scale of the First International Stroke Trial were used to assess outcome. We used multiple regression analysis. RESULTS: Before their stroke, 24.5% were smokers and 24.7% admitted regular alcohol consumption. Neither smoking nor alcohol consumption status was associated with initial stroke severity. Case fatalities at discharge, at 30 days, and at 1 year were 12.2%, 16.9%, and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and nonconsumers in 30-day and in 1-year case fatality in all strokepatients and in ischemic strokepatients. In hemorrhagic stroke, there was a nonsignificant tendency for higher case fatality among alcohol consumers (39.5% versus 26.4%, P > .2, at 30 days and 48.8% versus 35.8%, P > .2, at 1 year). Smoking did not influence significantly the outcome at 30 days and at 1 year. CONCLUSION: Despite being risk factors, prestroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long-term outcome.
Authors: Qianwen Zheng; Yawen Li; Lu Zhang; Qiang Yao; Jing Zhang; Mier Li; Ju Wang; Cairong Zhu Journal: Nan Fang Yi Ke Da Xue Xue Bao Date: 2019-04-30
Authors: Ju-Hun Lee; Ju Young Lee; So Hyun Ahn; Min Uk Jang; Mi Sun Oh; Chul-Ho Kim; Kyung-Ho Yu; Byung-Chul Lee Journal: J Stroke Date: 2015-05-29 Impact factor: 6.967