AIMS: The aim of this study was to investigate whether the shelf-life of diagnostic antibodies is longer than the expiry date on the label. METHODS AND RESULTS: Four independent laboratories tested a small number of diagnostic antibodies kept at +4°C for 12-26 years, and found them to work perfectly on routine histology sections. CONCLUSIONS: Diagnostic antibodies may have a workable half-life in excess of 10 years, and the emphasis on performance should shift to the preservation of antigenic targets in the tissue.
AIMS: The aim of this study was to investigate whether the shelf-life of diagnostic antibodies is longer than the expiry date on the label. METHODS AND RESULTS: Four independent laboratories tested a small number of diagnostic antibodies kept at +4°C for 12-26 years, and found them to work perfectly on routine histology sections. CONCLUSIONS: Diagnostic antibodies may have a workable half-life in excess of 10 years, and the emphasis on performance should shift to the preservation of antigenic targets in the tissue.
Authors: J J Bass; D J Wilkinson; D Rankin; B E Phillips; N J Szewczyk; K Smith; P J Atherton Journal: Scand J Med Sci Sports Date: 2016-06-05 Impact factor: 4.221
Authors: Gregg E Dinse; Christine G Parks; Clarice R Weinberg; Caroll A Co; Jesse Wilkerson; Darryl C Zeldin; Edward K L Chan; Frederick W Miller Journal: Arthritis Rheumatol Date: 2020-04-30 Impact factor: 15.483
Authors: R Tedjo Sasmono; Edison Johar; Benediktus Yohan; Chairin Nisa Ma'roef; Amin Soebandrio; Khin Sa Myint; Paul Pronyk; Sri Rezeki Hadinegoro; Elizabeth Jane Soepardi; Alain Bouckenooghe; William Hawley; Ronald Rosenberg; Ann M Powers Journal: Am J Trop Med Hyg Date: 2021-07-26 Impact factor: 2.345