Literature DB >> 2410194

Drug effects on the neovascularization response to silver nitrate cauterization of the rat cornea.

J M Mahoney, L D Waterbury.   

Abstract

Neovascular growth into the cornea induced by silver nitrate cauterization is the basis of this experimental model developed to test potential anti-inflammatory drugs for ocular use. Cauterization of the rat cornea with a silver nitrate applicator stick provides the stimulus for neovascularization, which is scored by a "blinded" investigator. Burn stimulus intensity is also scored to substantiate a consistent stimulus among the groups. Compounds showing activity in this model include topical dexamethasone, prednisolone, ticabesone propionate, ketorolac, and phenidone. This model is presented as a practical method for testing anti-inflammatory drugs in the eye.

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Year:  1985        PMID： 2410194     DOI： 10.3109/02713688508999984

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN： 0271-3683            Impact factor:   2.424


  22 in total

1.  Parstatin suppresses ocular neovascularization and inflammation.

Authors:  Hu Huang; Panagiotis Vasilakis; Xiufeng Zhong; Ji-Kui Shen; Katerina Geronatsiou; Helen Papadaki; Michael E Maragoudakis; Sotirios P Gartaganis; Stanley A Vinores; Nikos E Tsopanoglou
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-06-10       Impact factor: 4.799

2.  Laser photocoagulation for corneal stromal vascularization.

Authors:  V S Nirankari
Journal:  Trans Am Ophthalmol Soc       Date:  1992

3.  Inhibition of experimental corneal neovascularisation by bevacizumab (Avastin).

Authors:  Roberta P A Manzano; Gholam A Peyman; Palwasha Khan; Petros E Carvounis; Muhamet Kivilcim; Min Ren; Jonathan C Lake; Patricia Chévez-Barrios
Journal:  Br J Ophthalmol       Date:  2006-12-19       Impact factor: 4.638

4.  Angiogenic stimulation compared with angiogenic reaction to injury: distinction by focal and general application of trypsin to the chick chorioallantoic membrane.

Authors:  W D Thompson; M A Kazmi
Journal:  Br J Exp Pathol       Date:  1989-12

5.  Whole-body and intravital optical imaging of angiogenesis in orthotopically implanted tumors.

Authors:  M Yang; E Baranov; X M Li; J W Wang; P Jiang; L Li; A R Moossa; S Penman; R M Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-27       Impact factor: 11.205

Review 6.  Ketorolac. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential.

Authors:  M M Buckley; R N Brogden
Journal:  Drugs       Date:  1990-01       Impact factor: 9.546

7.  Topically administered bevacizumab had longer standing anti-angiogenic effect than subconjunctivally injected bevacizumab in rat corneal neovacularization.

Authors:  Jae Kim; Dong Kim; Eun-Soon Kim; Myoung Joon Kim; Hungwon Tchah
Journal:  Int J Ophthalmol       Date:  2013-10-18       Impact factor: 1.779

8.  Attenuation of corneal neovascularization by topical low-molecular-weight heparin-taurocholate 7 without bleeding complication.

Authors:  Jae Yong Kim; Soo Yeon Kim; Mi Hyun Cheon; Eun-Soon Kim; In Seok Song; Myoung Joon Kim; Hungwon Tchah
Journal:  Int J Ophthalmol       Date:  2016-09-18       Impact factor: 1.779

9.  Comparison of subconjunctivally injected bevacizumab, ranibizumab, and pegaptanib for inhibition of corneal neovascularization in a rat model.

Authors:  Ebru Eren Akar; Veysi Oner; Cem Küçükerdönmez; Yonca Aydın Akova
Journal:  Int J Ophthalmol       Date:  2013-04-18       Impact factor: 1.779

10.  Effect of subconjuctival and intraocular bevacizumab injection on angiogenic gene expression levels in a mouse model of corneal neovascularization.

Authors:  Olga Dratviman-Storobinsky; Bat-Chen R Avraham-Lubin; Murat Hasanreisoglu; Nitza Goldenberg-Cohen
Journal:  Mol Vis       Date:  2009-11-13       Impact factor: 2.367
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