Literature DB >> 24101590

Enamel defects on the maxillary premolars in patients with cleft lip and/or palate: a retrospective case-control study.

S Carpentier1, E Ghijselings, J Schoenaers, C Carels, A Verdonck.   

Abstract

AIM: The purpose of this study was to investigate the presence of developmental defects of enamel on maxillary premolars in patients with cleft lip and/or palate. In addition, the relationship with the surgical technique of soft palate closure was studied. Such a relationship could be suspected since formation of enamel occurs around the same time period as soft palate closure.
MATERIALS AND METHODS: The study consisted of three groups. Patients from the first group (n = 123) were recruited from the Cleft Lip and Palate Team of the University Hospitals Leuven (CLPT-UHL). The second group (n = 81) consisted of patients consulting the Cleft Lip and Palate Team of the Radboud University Medical Centre Nijmegen (CLPT-UMCN). Healthy non-cleft lip and/or palate patients (n = 100) recruited from a private orthodontic practice were enrolled in group 3. All maxillary premolars were examined.
RESULTS: Out of the total sample, 43 patients showed developmental defects on one or more premolars. All defects occurred in patients of group 1 who received surgical closure by the CLPT-UHL. None of the patients from group 2 and 3 showed defects.
CONCLUSIONS: It can be suggested that the surgical technique, used by the CLPT-UHL for soft palate closure, causes these defects. It is postulated that the technique used by the CLPT-UHL leads to interference with the blood supply of the developing premolar at a critical stage of tooth enamel development. More research is needed to confirm these findings.

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Year:  2013        PMID: 24101590     DOI: 10.1007/s40368-013-0078-8

Source DB:  PubMed          Journal:  Eur Arch Paediatr Dent        ISSN: 1818-6300


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