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Literature DB >> 241012

Studies of 3-aminopyridine adenine dinucleotide phosphate.

B M Anderson, J H Yuan, S V Vercellotti.

Abstract

3-Aminopyridine adenine dinucleotide phosphate (AADP) was prepared from NADP and 3-amino-pyridine through the pig brain NADase-catalyzed pyridine base exchange reaction. The purified dinucleotide was chemically characterized and spectral properties of the compound were determined. The importance of the application of AADP in studies of NADP-requiring biochemical processes was indicated by the demonstration of AADP as an effective inhibitor of five NADP-requiring enzymes, by the demonstration of the fluorescence enhancement on the binding of AADP to yeast glucose-6-phosphate dehydrogenase when glucose-6-phosphate is present, and by the functioning of AADP as a fluorimetric substrate for snake venom nucleotide pyrophosphatase.

Entities: Chemical Gene Species

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Year: 1975 PMID： 241012 DOI： 10.1007/bf02116237

Source DB: PubMed Journal: Mol Cell Biochem ISSN： 0300-8177 Impact factor: 3.396

13 in total

1. THE THIONICOTINAMIDE ANALOGS OF DPN AND TPN. I. PREPARATION AND ANALYSIS.

Authors: A M STEIN; J K LEE; C D ANDERSON; B M ANDERSON
Journal: Biochemistry Date: 1963 Sep-Oct Impact factor: 3.162

2. Inhibition of spleen diphosphopyridine nucleotidase by nicotinamide, an exchange reaction.

Authors: L J ZATMAN; N O KAPLAN; S P COLOWICK
Journal: J Biol Chem Date: 1953-01 Impact factor: 5.157

3. A spectrophotometric method for the analysis of the purine and pyrimidine components of ribonucleic acid.

Authors: H S LORING; J L FAIRLEY; H W BORTNER; H L SEAGRAN
Journal: J Biol Chem Date: 1952-05 Impact factor: 5.157

4. The prosthetic group of crystalline d-glyceraldehyde-3-phosphate dehydrogenase.

Authors: J F TAYLOR; S F VELICK
Journal: J Biol Chem Date: 1948-04 Impact factor: 5.157

5. Nuclear magnetic resonance studies on pyridine dinucleotides. I. The pH dependence of the carbon 13 nuclear magnetic resonance of nicotinamide adenine dinucleotide.

Authors: P D Ellis; R R Fisher; R B Dunlap; A P Zens; T A Bryson; T J Williams
Journal: J Biol Chem Date: 1973-11-25 Impact factor: 5.157

10. Investigation of the conformation of beta-diphosphopyridine nucleotide (beta-nicotinamide-adenine dinucleotide) and pyridine dinucleotide analogs by proton magnetic resonance.

Authors: R H Sarma; V Ross; N O Kaplan
Journal: Biochemistry Date: 1968-09 Impact factor: 3.162

3 in total

Studies of 3-aminopyridine adenine dinucleotide phosphate.

1. THE THIONICOTINAMIDE ANALOGS OF DPN AND TPN. I. PREPARATION AND ANALYSIS.

2. Inhibition of spleen diphosphopyridine nucleotidase by nicotinamide, an exchange reaction.

3. A spectrophotometric method for the analysis of the purine and pyrimidine components of ribonucleic acid.

4. The prosthetic group of crystalline d-glyceraldehyde-3-phosphate dehydrogenase.

5. Nuclear magnetic resonance studies on pyridine dinucleotides. I. The pH dependence of the carbon 13 nuclear magnetic resonance of nicotinamide adenine dinucleotide.

6. Bull semen nicotinamide adenine dinucleotide nucleosidase. 3. Properties of the substrate binding site.

7. The conformation of pyridine dinucleotides in solution.

8. Bull semen nicotinamide adenine dinucleotide nucleosidase. I. Purification and properties of the enzyme.

9. Bull semen nicotinamide adenine dinucleotide nucleosidase. V. Kinetic studies.

10. Investigation of the conformation of beta-diphosphopyridine nucleotide (beta-nicotinamide-adenine dinucleotide) and pyridine dinucleotide analogs by proton magnetic resonance.

1. Development of highly sensitive fluorescent assays for fatty acid amide hydrolase.

2. Studies of yeast alcohol dehydrogenase with 3-aminopyridine monucleotide.

3. Preparation of analogues of NAD+ as substrates for a sensitive fluorimetric assay of nucleotide pyrophosphatase.