| Literature DB >> 24100980 |
Abstract
A signaling cascade is activated in podocytes to induce survival and cope with stress during advanced glomerular disease, a new study shows. The findings may also explain why the immunosuppressor sirolimus, an inhibitor of this pathway, can cause proteinuria in a subset of patients with chronic kidney disease (pages 1288–1296).Entities:
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Year: 2013 PMID: 24100980 DOI: 10.1038/nm.3357
Source DB: PubMed Journal: Nat Med ISSN: 1078-8956 Impact factor: 53.440