PURPOSE OF REVIEW: With the availability of antiretroviral drugs in resource-limited settings, there is a rapid scale-up of antiretroviral therapy in developing countries. RECENT FINDINGS: The review focuses on the issues faced while patients are on first-line antiretroviral therapy in the absence of viral load monitoring, and the availability and progress of the second-line antiretroviral drugs and the salvage regimens in resource-limited settings. SUMMARY: There is an urgent need for low-cost, low-tech viral load monitoring in resource-limited settings. Fixed-dose combination of antiretrovirals for first-line and second-line therapy will result in better effectiveness. There is a need for newer antiretroviral drugs in resource-limited settings.
PURPOSE OF REVIEW: With the availability of antiretroviral drugs in resource-limited settings, there is a rapid scale-up of antiretroviral therapy in developing countries. RECENT FINDINGS: The review focuses on the issues faced while patients are on first-line antiretroviral therapy in the absence of viral load monitoring, and the availability and progress of the second-line antiretroviral drugs and the salvage regimens in resource-limited settings. SUMMARY: There is an urgent need for low-cost, low-tech viral load monitoring in resource-limited settings. Fixed-dose combination of antiretrovirals for first-line and second-line therapy will result in better effectiveness. There is a need for newer antiretroviral drugs in resource-limited settings.
Authors: Nicole L De La Mata; Nagalingeswaran Kumarasamy; Penh Sun Ly; Oon Tek Ng; Kinh Van Nguyen; Tuti Parwati Merati; Man Po Lee; Cuong Duy Do; Jun Yong Choi; Jeremy L Ross; Matthew G Law Journal: AIDS Care Date: 2017-01-29
Authors: Nicole L De La Mata; Nagalingeswaran Kumarasamy; Vohith Khol; Oon Tek Ng; Kinh Van Nguyen; Tuti Parwati Merati; Thuy Thanh Pham; Man Po Lee; Nicolas Durier; Matthew Law Journal: Antivir Ther Date: 2016-02-10
Authors: J Ross; A Jiamsakul; N Kumarasamy; I Azwa; T P Merati; C D Do; M P Lee; P S Ly; E Yunihastuti; K V Nguyen; R Ditangco; O T Ng; J Y Choi; S Oka; A H Sohn; M Law Journal: HIV Med Date: 2020-11-05 Impact factor: 3.180
Authors: Ivan Namakoola; Ivan Kasamba; Billy N Mayanja; Patrick Kazooba; Joseph Lutaakome; Fred Lyagoba; Anne A Kapaata; Pontiano Kaleebu; Paula Munderi Journal: BMC Res Notes Date: 2016-12-23
Authors: Marcelo J Wolff; Mark J Giganti; Claudia P Cortes; Pedro Cahn; Beatriz Grinsztejn; Jean W Pape; Denis Padgett; Juan Sierra-Madero; Eduardo Gotuzzo; Stephany N Duda; Catherine C McGowan; Bryan E Shepherd Journal: PLoS One Date: 2017-06-26 Impact factor: 3.240