Literature DB >> 24100587

One-pot, single-step deracemization of 2-hydroxyacids by tandem biocatalytic oxidation and reduction.

Ya-Ping Xue1, Yu-Guo Zheng, Ya-Qin Zhang, Jing-Lei Sun, Zhi-Qiang Liu, Yin-Chu Shen.   

Abstract

A facile and efficient one-pot, single-step method for deracemizing a broad range of 2-hydroxyacids to (R)-2-hydroxyacids was established by combination of resting cells of an (S)-hydroxyacid dehydrogenase-producing microorganism and an (R)-ketoacid reductase-producing microorganism.

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Year:  2013        PMID: 24100587     DOI: 10.1039/c3cc46240d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Enantioselective cascade biocatalysis for deracemization of 2-hydroxy acids using a three-enzyme system.

Authors:  Ya-Ping Xue; Hao Zeng; Xiao-Lu Jin; Zhi-Qiang Liu; Yu-Guo Zheng
Journal:  Microb Cell Fact       Date:  2016-09-22       Impact factor: 5.328

  1 in total

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