| Literature DB >> 24100350 |
David Jhf Knapp1, Connie J Eaves1.
Abstract
Several studies have demonstrated the clonal transmission of distinct differentiation and self-renewal properties in hematopoietic stem cells during the regeneration of blood production in transplanted recipients. A recent publication now identifies Vwf expression as a discriminating marker of a hematopoietic stem cell state that is primed for platelet production in response to thrombopoietin, but also subject to developmental and other, as yet undefined, cues.Entities:
Mesh:
Year: 2013 PMID: 24100350 PMCID: PMC3879699 DOI: 10.1038/cr.2013.139
Source DB: PubMed Journal: Cell Res ISSN: 1001-0602 Impact factor: 25.617