Hale Çolakoğlu Er1, Ayşe Erden, N Özlem Küçük, Ethem Geçim. 1. From the Departments of Radiology (H.Ç.E., A.E. e-mail: ayse.erden@medicine.ankara.edu.tr), Nuclear Medicine (N.Ö.K.), and General Surgery (E.G.), Ankara University School of Medicine, Ankara, Turkey.
Abstract
PURPOSE: The aim of this study was to retrospectively assess the correlation between minimum apparent diffusion coefficient (ADCmin) values obtained from diffusion-weighted magnetic resonance imaging (MRI) and maximum standardized uptake values (SUVmax) obtained from positron emission tomography-computed tomography (PET-CT) in rectal cancer. MATERIALS AND METHODS: Forty-one patients with pathologically confirmed rectal adenocarcinoma were included in this study. For preoperative staging, PET-CT and pelvic MRI with diffusion-weighted imaging were performed within one week (mean time interval, 3±1 day). For ADC measurements, the region of interest (ROI) was manually drawn along the border of each hyperintense tumor on b=1000 s/mm2 images. After repeating this procedure on each consecutive tumor-containing slice to cover the entire tumoral area, ROIs were copied to ADC maps. ADCmin was determined as the lowest ADC value among all ROIs in each tumor. For SUVmax measurements, whole-body images were assessed visually on transaxial, sagittal, and coronal images. ROIs were determined from the lesions observed on each slice, and SUVmax values were calculated automatically. The mean values of ADCmin and SUVmax were compared using Spearman's test. RESULTS: The mean ADCmin was 0.62±0.19×10-3 mm2/s (range, 0.368-1.227×10-3 mm2/s), the mean SUVmax was 20.07±9.3 (range, 4.3-49.5). A significant negative correlation was found between ADCmin and SUVmax (r=-0.347; P = 0.026). CONCLUSION: There was a significant negative correlation between the ADCmin and SUVmax values in rectal adenocarcinomas.
PURPOSE: The aim of this study was to retrospectively assess the correlation between minimum apparent diffusion coefficient (ADCmin) values obtained from diffusion-weighted magnetic resonance imaging (MRI) and maximum standardized uptake values (SUVmax) obtained from positron emission tomography-computed tomography (PET-CT) in rectal cancer. MATERIALS AND METHODS: Forty-one patients with pathologically confirmed rectal adenocarcinoma were included in this study. For preoperative staging, PET-CT and pelvic MRI with diffusion-weighted imaging were performed within one week (mean time interval, 3±1 day). For ADC measurements, the region of interest (ROI) was manually drawn along the border of each hyperintense tumor on b=1000 s/mm2 images. After repeating this procedure on each consecutive tumor-containing slice to cover the entire tumoral area, ROIs were copied to ADC maps. ADCmin was determined as the lowest ADC value among all ROIs in each tumor. For SUVmax measurements, whole-body images were assessed visually on transaxial, sagittal, and coronal images. ROIs were determined from the lesions observed on each slice, and SUVmax values were calculated automatically. The mean values of ADCmin and SUVmax were compared using Spearman's test. RESULTS: The mean ADCmin was 0.62±0.19×10-3 mm2/s (range, 0.368-1.227×10-3 mm2/s), the mean SUVmax was 20.07±9.3 (range, 4.3-49.5). A significant negative correlation was found between ADCmin and SUVmax (r=-0.347; P = 0.026). CONCLUSION: There was a significant negative correlation between the ADCmin and SUVmax values in rectal adenocarcinomas.
Authors: Barış Türkbey; Ömer Aras; Nevzat Karabulut; Ahmet Tuncay Turgut; Erhan Akpinar; Sedat Alibek; Yuxi Pang; Şükrü Mehmet Ertürk; Riham H El Khouli; David A Bluemke; Peter L Choyke Journal: Diagn Interv Radiol Date: 2011-09-19 Impact factor: 2.630
Authors: Eun Ja Lee; Karel terBrugge; David Mikulis; Dae Seob Choi; Jong Myon Bae; Seon Kyu Lee; Soon Young Moon Journal: AJR Am J Roentgenol Date: 2011-01 Impact factor: 3.959