| Literature DB >> 24098886 |
Stefano Persano1, Paola Valentini, Joong Hyun Kim, Pier Paolo Pompa.
Abstract
We developed a polymerase reaction free, low-cost and sensitive assay for the colorimetric detection of Human Papilloma Virus (HPV), based on the use of a smart design exploiting magnetic microbeads, chimeric RNA/DNAzyme oligonucleotides, and double signal amplification. This method allows obtaining a fast response with a detection limit of 10 pM, avoiding the amplification of the target via traditional PCR.Entities:
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Year: 2013 PMID： 24098886 DOI： 10.1039/c3cc45459b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222