Literature DB >> 24096067

Antioxidant activity and spectroscopic data of isoxanthohomol oxime and related compounds.

Bartłomiej Potaniec1, Małgorzata Grabarczyk, Monika Stompor, Antoni Szumny, Paweł Zieliński, Anna Katarzyna Żołnierczyk, Mirosław Anioł.   

Abstract

Oximes of isoxanthohumol (IXN), naringenin (N) and flavanone (FL) were synthesized with yields of 88-95% and their antioxidant activity was evaluated using the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) method. Although naringenin oxime (NOX) and flavanone oxime (FLOX) did not have any significant antioxidant effect (EC50=2.21 mM and 78.7 mM, respectively), isoxanthohumol oxime (IXNOX) showed a strong antioxidant activity (EC50=0.0411 mM), comparable to the activity of ascorbic acid (EC50=0.0181 mM). The structure of new compound IXNOX was established using (1)H NMR, (13)C NMR, IR and UV-VIS spectroscopy, by comparison to IXN, NOX and FLOX.
Copyright © 2013 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Antioxidant activity; DPPH method; Isoxanthohumol oxime; NMR–IR–UV spectra; Synergism

Mesh：

Substances：

Year:  2013        PMID： 24096067     DOI： 10.1016/j.saa.2013.09.018

Source DB:  PubMed          Journal:  Spectrochim Acta A Mol Biomol Spectrosc        ISSN： 1386-1425            Impact factor:   4.098


  8 in total

1.  Isoxanthohumol, a constituent of hop (Humulus lupulus L.), increases stress resistance in Caenorhabditis elegans dependent on the transcription factor DAF-16.

Authors:  Christian Büchter; Susannah Havermann; Karoline Koch; Wim Wätjen
Journal:  Eur J Nutr       Date:  2015-02-03       Impact factor: 5.614

2.  Synthesis and Biological Activity of Novel O-Alkyl Derivatives of Naringenin and Their Oximes.

Authors:  Joanna Kozłowska; Bartłomiej Potaniec; Barbara Żarowska; Mirosław Anioł
Journal:  Molecules       Date:  2017-09-06       Impact factor: 4.411

3.  Prevention of Fine Dust-Induced Vascular Senescence by Humulus lupulus Extract and Its Major Bioactive Compounds.

Authors:  Saugat Shiwakoti; Deepak Adhikari; Jeong Pyo Lee; Ki-Woon Kang; Ik-Soo Lee; Hyun Jung Kim; Min-Ho Oak
Journal:  Antioxidants (Basel)       Date:  2020-12-07

4.  Preparation of Synthetic and Natural Derivatives of Flavonoids Using Suzuki-Miyaura Cross-Coupling Reaction.

Authors:  Martina Hurtová; David Biedermann; Zuzana Osifová; Josef Cvačka; Kateřina Valentová; Vladimír Křen
Journal:  Molecules       Date:  2022-01-31       Impact factor: 4.411

5.  Appraisal of Total Phenol, Flavonoid Contents, and Antioxidant Potential of Folkloric Lannea coromandelica Using In Vitro and In Vivo Assays.

Authors:  Tekeshwar Kumar; Vishal Jain
Journal:  Scientifica (Cairo)       Date:  2015-09-17

6.  Synthesis and In Vitro Antitumor Activity of Naringenin Oxime and Oxime Ether Derivatives.

Authors:  Ahmed Dhahir Latif; Tímea Gonda; Máté Vágvölgyi; Norbert Kúsz; Ágnes Kulmány; Imre Ocsovszki; Zoltán Péter Zomborszki; István Zupkó; Attila Hunyadi
Journal:  Int J Mol Sci       Date:  2019-05-02       Impact factor: 5.923

7.  Antimicrobial O-Alkyl Derivatives of Naringenin and Their Oximes Against Multidrug-Resistant Bacteria.

Authors:  Anna Duda-Madej; Joanna Kozłowska; Paweł Krzyżek; Mirosław Anioł; Alicja Seniuk; Katarzyna Jermakow; Ewa Dworniczek
Journal:  Molecules       Date:  2020-08-10       Impact factor: 4.411

8.  Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress.

Authors:  Lidia Ciccone; Giovanni Petrarolo; Francesca Barsuglia; Carole Fruchart-Gaillard; Evelyne Cassar Lajeunesse; Adeniyi T Adewumi; Mahmoud E S Soliman; Concettina La Motta; Elisabetta Orlandini; Susanna Nencetti
Journal:  Biomolecules       Date:  2022-03-14
  8 in total

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