| Literature DB >> 24094895 |
Dong Wook Kim1, Young-Soo Jung, Hyung-Sik Park, Hwi-Dong Jung.
Abstract
Antiresorptive agent-related osteonecrosis of the jaw results in appreciable morbidity in affected patients. Nowadays many physicians prescribe an antiangiogenic agent for the management of malignant metastases. Everolimus is a serine-threonine kinase that acts as an inhibitor of mammalian target of rapamycin, which results in reduced growth of cells, angiogenesis, and survival of cells. We report the first case to our knowledge of osteonecrosis of the jaw that seemed to result from the additive effect of everolimus.Entities:
Keywords: ARONJ; Anti-angiogenic agent; Anti-resorptive agent related osteonecrosis of the jaw; Everolimus
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Year: 2013 PMID: 24094895 DOI: 10.1016/j.bjoms.2013.09.008
Source DB: PubMed Journal: Br J Oral Maxillofac Surg ISSN: 0266-4356 Impact factor: 1.651