| Literature DB >> 24094097 |
Chan Choo Yap1, Bettina Winckler.
Abstract
The sodium-proton exchanger NHE6 contributes to proper endosomal acidification. NHE6 mutations are also linked to autism-related disorders. In this issue of Neuron, using NHE6-knockout mice, Ouyang et al. (2013) uncover how dysregulation of endosomal pH leads to disturbances in BDNF signaling and neuronal morphogenesis defects.Entities:
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Year: 2013 PMID： 24094097 DOI： 10.1016/j.neuron.2013.09.018
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173