Literature DB >> 24092038

[Human herpesvirus 8 related Kaposi's sarcoma in a pediatric liver transplant recipient: case report].

Ivone Malla, Celeste Pérez, Yu Cheang, Marcelo Silva.   

Abstract

Patients under immunosuppressive treatment are at risk of developing malignant tumors. Primary infection or reactivation of human herpesvirus 8 (HHV-8) may predispose to Kaposi's sarcoma (KS) after solid organ transplantation. KS in pediatric liver transplant recipients has low incidence and poor prognosis. We report the clinical presentation of a KS in lymph node following HHV-8 infection in a pediatric patient presenting four months after liver transplantation. He had a good outcome with suspension of tacrolimus and conversion to sirolimus one month after diagnosis. To our knowledge, this is the frst KS reported case in our country after liver transplant in a pediatric recipient and we believe that this entity should be taken into consideration in the differential diagnosis of post-transplant complications.

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Year:  2013        PMID: 24092038     DOI: 10.5546/aap.2013.e125

Source DB:  PubMed          Journal:  Arch Argent Pediatr        ISSN: 0325-0075            Impact factor:   0.694


  1 in total

Review 1.  Kaposi Sarcoma of Childhood: Inborn or Acquired Immunodeficiency to Oncogenic HHV-8.

Authors:  Carolyn C Jackson; Mark A Dickson; Mahan Sadjadi; Antoine Gessain; Laurent Abel; Emmanuelle Jouanguy; Jean-Laurent Casanova
Journal:  Pediatr Blood Cancer       Date:  2015-10-15       Impact factor: 3.167

  1 in total

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