Literature DB >> 24091700

Highly enantioselective iron(II)-catalyzed opening reaction of aromatic meso-epoxides with indoles.

Baptiste Plancq1, Mathieu Lafantaisie, Simon Companys, Cendrella Maroun, Thierry Ollevier.   

Abstract

A highly enantioselective method for the catalytic cis-stilbene oxide opening reaction with indole derivatives was developed. The scope of the reaction was studied with a selection of aromatic meso-epoxides and various indoles, and the desired 2-(indol-3-yl)ethanol derivatives were obtained in good to excellent yields with excellent enantioselectivities (from 96 to >99% ee).

Entities:  

Year:  2013        PMID: 24091700     DOI: 10.1039/c3ob41782d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Oxidative Cleavage of Alkene C=C Bonds Using a Manganese Catalyzed Oxidation with H2O2 Combined with Periodate Oxidation.

Authors:  Francesco Mecozzi; Jia Jia Dong; Davide Angelone; Wesley R Browne; Niek N H M Eisink
Journal:  European J Org Chem       Date:  2019-10-31
  1 in total

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