| Literature DB >> 24091639 |
Tuan Minh Nguyen1, Hung A Duong, Jean-Alexandre Richard, Charles William Johannes, Fu Pincheng, Danson Kwong Jia Ye, Eileen Lau Shuying.
Abstract
Cascade fluorofunctionalisation of 2,3-unsubstituted indoles featuring the formation of C-C, C-F and C-O bonds via electrophilic fluorination using N-fluorobenzenesulfonimide is described. The use of an O-nucleophile tethered to the nitrogen of indoles enables the synthesis of polycyclic fluorinated indoline derivatives from simple precursors in 40-63% yields.Entities:
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Year: 2013 PMID： 24091639 DOI： 10.1039/c3cc46564k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222