Literature DB >> 24091489

Economic analysis and review of the literature on implant-based breast reconstruction with and without the use of the acellular dermal matrix.

Jonathan Bank1, Nicole A Phillips, Julie E Park, David H Song.   

Abstract

BACKGROUND: Use of the acellular dermal matrix (ADM) in two-stage implant-based breast reconstruction has been widely adopted. Despite an increasing focus on health care costs, few reports have addressed the financial implications of ADM use. This study sought to examine the costs of the two-stage technique with and without ADM, concentrating on the direct variable costs of patient care during the expansion process.
METHODS: A retrospective review of a prospectively maintained database was conducted. Data were collected on 132 cases resulting in a second-stage exchange for a permanent implant. The findings showed that AlloDerm was used in 61 reconstructions and Strattice in 23 reconstructions. The primary outcome was the number of fills required to achieve the final expander fill volume. The cost of subsequent patient encounters for expansion was estimated using institutional cost data.
RESULTS: The number of fills required to achieve the final volume was higher in the non-ADM group (6.5 ± 1.7) than in the ADM group (3.6 ± 1.4) (p < 0.0001). No significant difference was found in the small fill volumes (<350 ml; 5.3 vs. 3.7; p > 0.05). The difference was significant in the larger fill volumes (>500 ml; 8.3 vs. 3.7; p < 0.05). Relative to non-ADM reconstruction, with AlloDerm at current prices, the cost increase ranged from $2,727.75 for large reconstructions to $3,290.25 for small reconstructions ($2,167.75-$2,739.25 with Strattice).
CONCLUSION: The use of ADM in two-stage reconstruction reduces the number of visits required for reconstructions with 350 ml or more. However, at current pricings, the direct cost of ADM use does not offset the cost savings from the reduced number of visits. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

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Year:  2013        PMID: 24091489     DOI: 10.1007/s00266-013-0213-2

Source DB:  PubMed          Journal:  Aesthetic Plast Surg        ISSN: 0364-216X            Impact factor:   2.326


  12 in total

Review 1.  Current opinions on indications and algorithms for acellular dermal matrix use in primary prosthetic breast reconstruction.

Authors:  Michael M Vu; John Y S Kim
Journal:  Gland Surg       Date:  2015-06

2.  Acellular Dermal Matrix in Immediate Expander/Implant Breast Reconstruction: A Multicenter Assessment of Risks and Benefits.

Authors:  Michael Sorkin; Ji Qi; Hyungjin M Kim; Jennifer B Hamill; Jeffrey H Kozlow; Andrea L Pusic; Edwin G Wilkins
Journal:  Plast Reconstr Surg       Date:  2017-12       Impact factor: 4.730

3.  A Head to Head Comparison Between SurgiMend® - Fetal Bovine Acellular Dermal Matrix and Tutomesh® - A Bovine Pericardium Collagen Membrane in Breast Reconstruction in 45 Cases.

Authors:  Christian Eichler; Jeria Efremova; Klaus Brunnert; Christian M Kurbacher; Oleg Gluz; Julian Puppe; Mathias Warm
Journal:  In Vivo       Date:  2017 Jul-Aug       Impact factor: 2.155

Review 4.  Regenerative and engineered options for urethroplasty.

Authors:  Filippo Pederzoli; Gregory Joice; Andrea Salonia; Trinity J Bivalacqua; Nikolai A Sopko
Journal:  Nat Rev Urol       Date:  2019-06-06       Impact factor: 14.432

5.  A Head-to-head Comparison between SurgiMend and Epiflex in 127 Breast Reconstructions.

Authors:  Christian Eichler; Nadine Vogt; Klaus Brunnert; Axel Sauerwald; Julian Puppe; Mathias Warm
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-07-08

6.  Prepectoral Implant-Based Breast Reconstruction.

Authors:  Lyndsey Highton; Richard Johnson; Cliona Kirwan; John Murphy
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-09-19

7.  Alternatives to Acellular Dermal Matrix: Utilization of a Gore DualMesh Sling as a Cost-Conscious Adjunct for Breast Reconstruction.

Authors:  Jacob N Grow; James Butterworth; Paul Petty
Journal:  Eplasty       Date:  2017-02-10

Review 8.  Novel devices for implant-based breast reconstruction: is the use of meshes to support the lower pole justified in terms of benefits? A review of the evidence.

Authors:  Lorna Jane Cook; Tibor Kovacs
Journal:  Ecancermedicalscience       Date:  2018-01-10

9.  Disparities in Access to Autologous Breast Reconstruction.

Authors:  David J Restrepo; Maria T Huayllani; Daniel Boczar; Andrea Sisti; Minh-Doan T Nguyen; Jordan J Cochuyt; Aaron C Spaulding; Brian D Rinker; Galen Perdikis; Antonio J Forte
Journal:  Medicina (Kaunas)       Date:  2020-06-08       Impact factor: 2.430

10.  A Randomized Controlled Trial Comparing Alloderm-RTU with DermACELL in Immediate Subpectoral Implant-Based Breast Reconstruction.

Authors:  Angel Arnaout; Jing Zhang; Simon Frank; Moein Momtazi; Erin Cordeiro; Amanda Roberts; Ammara Ghumman; Dean Fergusson; Carol Stober; Gregory Pond; Ahwon Jeong; Lisa Vandermeer; Brian Hutton; Mark Clemons
Journal:  Curr Oncol       Date:  2020-12-25       Impact factor: 3.677

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