OBJECTIVES: The aim of the study was to compare total and regional body composition and their relationship with glucose homeostasis in physically active and non-active individuals with cervical spinal cord injury (c-SCI). METHODS: Individuals with lesion level between C5-C7 were divided into two groups: physically active (PA; n = 14; who practiced physical exercise for at least 3 months, three times per week or more, minimum of 150 minutes/week): and non-physically active (N-PA n = 8). Total fat mass (t-FM) and regional fat mass (r-FM) were assessed by dual energy X-ray absorptiometry. Fasting plasma insulin (FPI) was determined by enzyme-linked immunosorbent assay. RESULTS: PA group present lower (P < 0.01) total fat mass (t-FM), % and kg, regional fat mass (r-FM), % and kg, FPI levels and HOMA index, while they had higher (P < 0.001) total free fat mass (t-FFM), %, and regional free fat mass (r-FFM), %, compared to the N-PA group. In the N-PA group, FPI and HOMA index were negatively (P < 0.05) correlated with FFM% (r = -0.71, -0.69, respectively) and positively correlated to trunk-FM (r = 0.71, 0.69, respectively) and trunk-FM:t-FM (kg) ratio (r = 0.83, 0.79, respectively). CONCLUSION: Physical exercise is associated with lower t-FM, r-FM, and insulin resistance, which could contribute to the decrease of the risk of cardiovascular and metabolic conditions in individuals with c-SCI.
OBJECTIVES: The aim of the study was to compare total and regional body composition and their relationship with glucose homeostasis in physically active and non-active individuals with cervical spinal cord injury (c-SCI). METHODS: Individuals with lesion level between C5-C7 were divided into two groups: physically active (PA; n = 14; who practiced physical exercise for at least 3 months, three times per week or more, minimum of 150 minutes/week): and non-physically active (N-PA n = 8). Total fat mass (t-FM) and regional fat mass (r-FM) were assessed by dual energy X-ray absorptiometry. Fasting plasma insulin (FPI) was determined by enzyme-linked immunosorbent assay. RESULTS: PA group present lower (P < 0.01) total fat mass (t-FM), % and kg, regional fat mass (r-FM), % and kg, FPI levels and HOMA index, while they had higher (P < 0.001) total free fat mass (t-FFM), %, and regional free fat mass (r-FFM), %, compared to the N-PA group. In the N-PA group, FPI and HOMA index were negatively (P < 0.05) correlated with FFM% (r = -0.71, -0.69, respectively) and positively correlated to trunk-FM (r = 0.71, 0.69, respectively) and trunk-FM:t-FM (kg) ratio (r = 0.83, 0.79, respectively). CONCLUSION: Physical exercise is associated with lower t-FM, r-FM, and insulin resistance, which could contribute to the decrease of the risk of cardiovascular and metabolic conditions in individuals with c-SCI.
Entities:
Keywords:
Cervical injury; Insulin; Physical activity; Regional fat mass
Authors: S R Smith; J C Lovejoy; F Greenway; D Ryan; L deJonge; J de la Bretonne; J Volafova; G A Bray Journal: Metabolism Date: 2001-04 Impact factor: 8.694
Authors: Ann M Spungen; Rodney H Adkins; Charles A Stewart; Jack Wang; Richard N Pierson; Robert L Waters; William A Bauman Journal: J Appl Physiol (1985) Date: 2003-08-08
Authors: Jacob A Goldsmith; Areej N Ennasr; Gary J Farkas; David R Gater; Ashraf S Gorgey Journal: Eur J Appl Physiol Date: 2021-04-23 Impact factor: 3.078
Authors: Gary J Farkas; Phillip S Gordon; Nareka Trewick; Ashraf S Gorgey; David R Dolbow; Eduard Tiozzo; Arthur S Berg; David R Gater Journal: J Clin Med Date: 2021-11-28 Impact factor: 4.241
Authors: Melody N Mickens; Paul Perrin; Jacob A Goldsmith; Refka E Khalil; William E Carter Iii; Ashraf S Gorgey Journal: Neural Regen Res Date: 2022-06 Impact factor: 5.135