| Literature DB >> 24090119 |
Yu-Lin Sun1, Xiao-Yong Zhang, Zhi-Hui Zheng, Xin-Ya Xu, Shu-Hua Qi.
Abstract
Three new polyketides penicitrinol G (1), penicitrinol H (2) and 2,11-dihydroxy-1-methoxycarbonyl-9-carboxylxanthone (3) together with one known cathepsin B inhibitor chrysophanol (4) were isolated from a culture broth of marine-derived fungus Penicillium citrinum SCSGAF 0167. Their structures were determined by spectroscopic methods. Compound 4 exhibited inhibitory activity against cathepsin B with IC50 value of 1.7 μM.Entities:
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Year: 2013 PMID： 24090119 DOI： 10.1080/14786419.2013.843177
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861