Literature DB >> 24089207

Cancer: Killing from the inside.

Paul Saftig, Konrad Sandhoff.   

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Year:  2013        PMID： 24089207     DOI： 10.1038/nature12692

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  10 in total

Review 1.  Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications.

Authors:  Johannes Kornhuber; Philipp Tripal; Martin Reichel; Christiane Mühle; Cosima Rhein; Markus Muehlbacher; Teja W Groemer; Erich Gulbins
Journal:  Cell Physiol Biochem       Date:  2010-05-18

Review 2.  Lysosomal membrane permeabilization in cell death.

Authors:  P Boya; G Kroemer
Journal:  Oncogene       Date:  2008-10-27       Impact factor: 9.867

Review 3.  Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function.

Authors:  Paul Saftig; Judith Klumperman
Journal:  Nat Rev Mol Cell Biol       Date:  2009-08-12       Impact factor: 94.444

4.  Stimulation of acid sphingomyelinase activity by lysosomal lipids and sphingolipid activator proteins.

Authors:  T Linke; G Wilkening; S Lansmann; H Moczall; O Bartelsen; J Weisgerber; K Sandhoff
Journal:  Biol Chem       Date:  2001-02       Impact factor: 3.915

Review 5.  Cysteine cathepsins: multifunctional enzymes in cancer.

Authors:  Mona Mostafa Mohamed; Bonnie F Sloane
Journal:  Nat Rev Cancer       Date:  2006-10       Impact factor: 60.716

6.  Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

Authors:  Thomas Kirkegaard; Anke G Roth; Nikolaj H T Petersen; Ajay K Mahalka; Ole Dines Olsen; Irina Moilanen; Alicja Zylicz; Jens Knudsen; Konrad Sandhoff; Christoph Arenz; Paavo K J Kinnunen; Jesper Nylandsted; Marja Jäättelä
Journal:  Nature       Date:  2010-01-28       Impact factor: 49.962

7.  Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion.

Authors:  Misbaudeen Abdul-Hammed; Bernadette Breiden; Matthew A Adebayo; Jonathan O Babalola; Günter Schwarzmann; Konrad Sandhoff
Journal:  J Lipid Res       Date:  2010-02-23       Impact factor: 5.922

8.  Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2.

Authors:  Nicole Fehrenbacher; Lone Bastholm; Thomas Kirkegaard-Sørensen; Bo Rafn; Trine Bøttzauw; Christina Nielsen; Ekkehard Weber; Senji Shirasawa; Tuula Kallunki; Marja Jäättelä
Journal:  Cancer Res       Date:  2008-08-15       Impact factor: 12.701

9.  The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts.

Authors:  R Hurwitz; K Ferlinz; K Sandhoff
Journal:  Biol Chem Hoppe Seyler       Date:  1994-07

10.  Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.

Authors:  Nikolaj H T Petersen; Ole D Olsen; Line Groth-Pedersen; Anne-Marie Ellegaard; Mesut Bilgin; Susanne Redmer; Marie S Ostenfeld; Danielle Ulanet; Tobias H Dovmark; Andreas Lønborg; Signe D Vindeløv; Douglas Hanahan; Christoph Arenz; Christer S Ejsing; Thomas Kirkegaard; Mikkel Rohde; Jesper Nylandsted; Marja Jäättelä
Journal:  Cancer Cell       Date:  2013-09-09       Impact factor: 31.743
  10 in total
  17 in total

Review 1.  Insight into nanoparticle cellular uptake and intracellular targeting.

Authors:  Basit Yameen; Won Il Choi; Cristian Vilos; Archana Swami; Jinjun Shi; Omid C Farokhzad
Journal:  J Control Release       Date:  2014-06-28       Impact factor: 9.776

2.  GNS561, a new lysosomotropic small molecule, for the treatment of intrahepatic cholangiocarcinoma.

Authors:  Sonia Brun; Firas Bassissi; Cindy Serdjebi; Marie Novello; Jennifer Tracz; François Autelitano; Marie Guillemot; Philippe Fabre; Jérôme Courcambeck; Christelle Ansaldi; Eric Raymond; Philipe Halfon
Journal:  Invest New Drugs       Date:  2019-02-19       Impact factor: 3.850

Review 3.  Lysosomal Biology in Cancer.

Authors:  Colin Fennelly; Ravi K Amaravadi
Journal:  Methods Mol Biol       Date:  2017

Review 4.  Targeting tumour-supportive cellular machineries in anticancer drug development.

Authors:  Matthias Dobbelstein; Ute Moll
Journal:  Nat Rev Drug Discov       Date:  2014-03       Impact factor: 84.694

Review 5.  Targeting the lysosome in cancer.

Authors:  Shengfu Piao; Ravi K Amaravadi
Journal:  Ann N Y Acad Sci       Date:  2015-11-24       Impact factor: 5.691

6.  Heat shock protein 70.1 (Hsp70.1) affects neuronal cell fate by regulating lysosomal acid sphingomyelinase.

Authors:  Hong Zhu; Tanihiro Yoshimoto; Tetsumori Yamashima
Journal:  J Biol Chem       Date:  2014-07-29       Impact factor: 5.157

7.  Highly stable and sensitive fluorescent probes (LysoProbes) for lysosomal labeling and tracking.

Authors:  Nazmiye B Yapici; Yue Bi; Pengfei Li; Xin Chen; Xin Yan; Srinivas Rao Mandalapu; Megan Faucett; Steffen Jockusch; Jingfang Ju; K Michael Gibson; William J Pavan; Lanrong Bi
Journal:  Sci Rep       Date:  2015-02-26       Impact factor: 4.379

8.  Crystal structure of mammalian acid sphingomyelinase.

Authors:  Alexei Gorelik; Katalin Illes; Leonhard X Heinz; Giulio Superti-Furga; Bhushan Nagar
Journal:  Nat Commun       Date:  2016-07-20       Impact factor: 14.919

9.  Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.

Authors:  Rushika M Perera; Svetlana Stoykova; Brandon N Nicolay; Kenneth N Ross; Julien Fitamant; Myriam Boukhali; Justine Lengrand; Vikram Deshpande; Martin K Selig; Cristina R Ferrone; Jeff Settleman; Gregory Stephanopoulos; Nicholas J Dyson; Roberto Zoncu; Sridhar Ramaswamy; Wilhelm Haas; Nabeel Bardeesy
Journal:  Nature       Date:  2015-07-13       Impact factor: 49.962

10.  Lysosomal targeting with stable and sensitive fluorescent probes (Superior LysoProbes): applications for lysosome labeling and tracking during apoptosis.

Authors:  Xin Chen; Yue Bi; Tianyang Wang; Pengfei Li; Xin Yan; Shanshan Hou; Catherine E Bammert; Jingfang Ju; K Michael Gibson; William J Pavan; Lanrong Bi
Journal:  Sci Rep       Date:  2015-03-11       Impact factor: 4.379
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