| Literature DB >> 2408856 |
L Lanfumey, C Dugovic, J Adrien.
Abstract
The influences of beta adrenergic transmission on the regulation of paradoxical sleep (PS) were analysed in the rat. Pharmacological experiments have used beta 1,2 as well as preferential beta 1 or beta 2 compounds. The blockade of the beta 1 adrenoceptors induced a dose-related PS decrease, and stimulation of these preblocked receptors prevented this PS insomnia. SWS was generally not affected. It is concluded that beta 1 neurotransmission is directly involved in the regulation of PS.Entities:
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Year: 1985 PMID： 2408856 DOI： 10.1016/0013-4694(85)91117-4
Source DB: PubMed Journal: Electroencephalogr Clin Neurophysiol ISSN： 0013-4694