INTRODUCTION: Phenols are the most abundant compounds in nature. They are strong antioxidants. Too high level of free radicals leads to cell and tissue damage, which may cause asthma, Alzheimer disease, cancers, etc. Taking phenolics with the diet as supplements or natural medicines is important for homeostasis of the organism. MATERIALS AND METHODS: The ten most popular water soluble phenols were chosen for the experiment to investigate their antioxidant properties using ABTS radical scavenging capacity assay and ferric reducing antioxidant potential (FRAP) assay. RESULTS AND DISCUSSION: Antioxidant properties of selected phenols in the ABTS test expressed as IC50 ranged from 4.332 μM to 852.713 μM (for gallic acid and 4- hydroxyphenylacetic acid respectively). Antioxidant properties in the FRAP test are expressed as μmol Fe2+/ml. All examined phenols reduced ferric ions at concentration 1.00 x 10-3 mg/ml. Both methods are very useful for determination of antioxidant capacity of water soluble phenols.
INTRODUCTION:Phenols are the most abundant compounds in nature. They are strong antioxidants. Too high level of free radicals leads to cell and tissue damage, which may cause asthma, Alzheimer disease, cancers, etc. Taking phenolics with the diet as supplements or natural medicines is important for homeostasis of the organism. MATERIALS AND METHODS: The ten most popular water soluble phenols were chosen for the experiment to investigate their antioxidant properties using ABTS radical scavenging capacity assay and ferric reducing antioxidant potential (FRAP) assay. RESULTS AND DISCUSSION: Antioxidant properties of selected phenols in the ABTS test expressed as IC50 ranged from 4.332 μM to 852.713 μM (for gallic acid and 4- hydroxyphenylacetic acid respectively). Antioxidant properties in the FRAP test are expressed as μmol Fe2+/ml. All examined phenols reduced ferric ions at concentration 1.00 x 10-3 mg/ml. Both methods are very useful for determination of antioxidant capacity of water soluble phenols.
Authors: Bruno Moukette Moukette; Constant Anatole Pieme; Prosper Cabral Nya Biapa; Jacques Romain Njimou; Vicky Jocelyne Ama Moor; Marco Stoller; Marco Bravi; Jeanne Yonkeu Ngogang Journal: Antioxidants (Basel) Date: 2014-12-16
Authors: Nur Zuliani Ramli; Kok-Yong Chin; Khairul Anwar Zarkasi; Fairus Ahmad Journal: Int J Environ Res Public Health Date: 2019-12-07 Impact factor: 3.390
Authors: Sunmin Lee; Dong-Gu Oh; Digar Singh; Hye Jin Lee; Ga Ryun Kim; Sarah Lee; Jong Seok Lee; Choong Hwan Lee Journal: Metabolites Date: 2019-09-16