Malignant glomus tumor of the esophagus with mediastinal lymph node metastases.

Extracutaneous malignant glomus tumors are unusual, and their occurrence in the esophagus has been recognized with extreme rarity. We describe a 47-year-old man who presented with progressive dysphagia and weight loss. Upper gastrointestinal endoscopy, a barium esophagram, and chest computed tomography revealed an unusually large, aggressive soft mass at the middle portion of the esophagus. A curative resection (R0 resection) was achieved by means of Ivor-Lewis esophagectomy and mediastinal lymph node dissection. The histopathologic examination and immunohistochemical studies demonstrated a malignant glomus tumor of the esophagus with mediastinal lymph node metastases.