CONTEXT: This study was designed to compare the sensitivities of different investigations for the diagnosis of Community Acquired Pneumonia (CAP). A prospective study was carried out which compared the sensitivities of the chest radiographs, CRP, TLC, ESR and the blood cultures in sixty-six patients who were diagnosed with WHO defined CAP. METHOD AND MATERIAL: The chest radiographs, serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), total leucocyte count (TLC) and blood cultures were determined in sixty-six patients who were amongst the age group of one month to five years of age, who were diagnosed with WHO defined CAP. STATISTICAL ANALYSIS: It was carried out by calculating the proportion, mean, standard deviation (SD) and the sensitivity of the test/.able RESULTS: The chest radiographs were found to be positive in 93.9% (n=62) patients, CRP was positive in 90.9% (n=60) patients, ESR was positive in 72.7% (n=42) patients, TLC was positive in 48.5% (n=38) patients and the blood cultures were positive in 6.1% (n=4) patients. Hence, the sensitivity of the chest radiograph, CRP, ESR, TLC and the blood culture in the diagnosis of CAP were 93.9%, 90.9%, 72.7%, 48.5% and 6.1%. CONCLUSION: In view of the high sensitivity of CRP, which is almost similar to that of chest X-Ray in detecting CAP, CRP can be used as an alternative test to the chest radiographs at peripheral centres, where X-ray machines are not available.
CONTEXT: This study was designed to compare the sensitivities of different investigations for the diagnosis of Community Acquired Pneumonia (CAP). A prospective study was carried out which compared the sensitivities of the chest radiographs, CRP, TLC, ESR and the blood cultures in sixty-six patients who were diagnosed with WHO defined CAP. METHOD AND MATERIAL: The chest radiographs, serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), total leucocyte count (TLC) and blood cultures were determined in sixty-six patients who were amongst the age group of one month to five years of age, who were diagnosed with WHO defined CAP. STATISTICAL ANALYSIS: It was carried out by calculating the proportion, mean, standard deviation (SD) and the sensitivity of the test/.able RESULTS: The chest radiographs were found to be positive in 93.9% (n=62) patients, CRP was positive in 90.9% (n=60) patients, ESR was positive in 72.7% (n=42) patients, TLC was positive in 48.5% (n=38) patients and the blood cultures were positive in 6.1% (n=4) patients. Hence, the sensitivity of the chest radiograph, CRP, ESR, TLC and the blood culture in the diagnosis of CAP were 93.9%, 90.9%, 72.7%, 48.5% and 6.1%. CONCLUSION: In view of the high sensitivity of CRP, which is almost similar to that of chest X-Ray in detecting CAP, CRP can be used as an alternative test to the chest radiographs at peripheral centres, where X-ray machines are not available.
Authors: Samir S Shah; Maria H Dugan; Louis M Bell; Robert W Grundmeier; Todd A Florin; Elizabeth M Hines; Joshua P Metlay Journal: Pediatr Infect Dis J Date: 2011-06 Impact factor: 2.129
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Authors: Enitan D Carrol; Limangeni A Mankhambo; Graham Jeffers; Deborah Parker; Malcolm Guiver; Paul Newland; Daniel L Banda; Elizabeth M Molyneux; Robert S Heyderman; Malcolm E Molyneux; C Anthony Hart Journal: PLoS One Date: 2009-08-13 Impact factor: 3.240
Authors: Ga Ram Kim; Min Sun Na; Kyung Suk Baek; Seung Jin Lee; Kyung Suk Lee; Young Ho Jung; Hye Mi Jee; Tae Hee Kwon; Man Yong Han; Youn Ho Sheen Journal: Korean J Pediatr Date: 2016-12-31